{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T07:18:22Z","timestamp":1769584702841,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,12,8]],"date-time":"2006-12-08T00:00:00Z","timestamp":1165536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Myracrodruon urundeuva<\/jats:italic> Allem\u00e3o is a plant utilized in Northeast Brazil as an antiinflammatory, wound healing and in gynecological illnesses. The objectives of the present study were to evaluate the antiinflammatory and antiulcer properties of the tannin\u2010enriched fraction (TEF) isolated from the stem bark of <jats:italic>M. urundeuva<\/jats:italic>, in the formalin test, in mice, and in carrageenan\u2010induced paw edema and gastric ulcer models, in rats. The results showed that TEF dose\u2010dependently inhibited both phases of the formalin test. However, the effect was predominant in the 2nd phase of the response where inhibitions of 47%, 76% and 85% were observed, with doses of 5, 10 and 50 mg\/kg, i.p. In the carrageenan\u2010induced paw edema, significant inhibitions were observed at 3 h (44%) and 4 h (28%), with a dose of 10 mg\/kg, i.p. TEF also significantly decreased by 37%, 43% and 57% gastric ulceration induced by indomethacin, at doses of 10, 20 and 50 mg\/kg p.o. In the ethanol\u2010induced gastric ulcer model, TEF was less effective, and significant inhibitions (42% to 46%) were observed only with doses of 100 and 200 mg\/kg, p.o., respectively. In conclusion, it was shown that TEF presents antiinflammatory and antiulcer effects, partly due to its antioxidant action, known to be present in polyphenols, including tannins. Copyright \u00a9 2006 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.2011","type":"journal-article","created":{"date-parts":[[2006,12,8]],"date-time":"2006-12-08T10:50:26Z","timestamp":1165575026000},"page":"220-225","source":"Crossref","is-referenced-by-count":87,"title":["Antiinflammatory and antiulcer properties of tannins from <i>Myracrodruon urundeuva<\/i> Allem\u00e3o (Anacardiaceae) in Rodents"],"prefix":"10.1002","volume":"21","author":[{"given":"S. M. C.","family":"Souza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. C. 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