{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T13:15:53Z","timestamp":1782911753345,"version":"3.54.5"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2007,4,2]],"date-time":"2007-04-02T00:00:00Z","timestamp":1175472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The <jats:italic>in vitro<\/jats:italic> and <jats:italic>in vivo<\/jats:italic> antioxidant activity of different extracts of leaves and root of parsley (<jats:italic>Petroselinum crispum<\/jats:italic> (Mill.) Nym. ex A.W. Hill, Apiaceae) were studied. Free radical scavenging capacity (RSC) was evaluated measuring the scavenging activity on the 2,2\u2010diphenyl\u20101\u2010picrylhydrazil (DPPH) and OH radicals. Also, the effects on lipid peroxidation (LP) were evaluated. The results obtained showed that all examined extracts act as good scavengers of DPPH and OH radicals and reduce the intensity of LP. The <jats:italic>in vivo<\/jats:italic> effects were evaluated on some antioxidant systems (activities of LPx, GSH\u2010Px, Px, CAT and XOD, and GSH content) in the mice liver and blood after treatment with the examined parsley extracts, or in combination with carbon tetrachloride (CCl<jats:sub>4<\/jats:sub>). On the basis of the results obtained it can be concluded that the examined extracts exhibited a certain protective effect. However, combined treatments with CCl<jats:sub>4<\/jats:sub> and the examined extracts showed both positive and negative synergism, inducing or suppressing the influence of CCl<jats:sub>4<\/jats:sub> alone. Copyright \u00a9 2007 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.2134","type":"journal-article","created":{"date-parts":[[2007,4,2]],"date-time":"2007-04-02T11:56:19Z","timestamp":1175514979000},"page":"717-723","source":"Crossref","is-referenced-by-count":32,"title":["Effect of parsley (<i>Petroselinum crispum<\/i> (Mill.) Nym. ex A.W. Hill, Apiaceae) extracts on some biochemical parameters of oxidative stress in mice treated with CCl<sub>4<\/sub>"],"prefix":"10.1002","volume":"21","author":[{"given":"Mira","family":"Popovi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biljana","family":"Kaurinovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vida","family":"Jakovljevi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neda","family":"Mimica\u2010Dukic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Bursa\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(89)90410-3"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(97)00458-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0021-9258(19)50881-X","article-title":"Spectrophotometric method for measuring of breakdown of hydrogen peroxide by catalase","volume":"195","author":"Beers RFJ","year":"1950","journal-title":"J Biol Chem"},{"key":"e_1_2_1_5_1","first-page":"483","volume-title":"Methoden Der Enzymatischen Analyse.","author":"Bergmayer UH","year":"1970"},{"key":"e_1_2_1_6_1","first-page":"882","article-title":"Improved methods for the determination of blood glutathione","volume":"61","author":"Beuthler E","year":"1983","journal-title":"J Lab Clin Med"},{"key":"e_1_2_1_7_1","volume-title":"The Complete German Commission E Monographs","author":"Blumenthal M","year":"1999"},{"key":"e_1_2_1_8_1","volume-title":"British Herbal Compendium. 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