{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T04:18:55Z","timestamp":1783657135263,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T00:00:00Z","timestamp":1205366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Mycobacterium tuberculosis<\/jats:italic> is a serious worldwide health threat, killing almost 2 million people per year. Alternative antimycobacterial drugs are urgently needed; studies have shown that medicinal plants traditionally used to treat respiratory diseases are a potential source of compounds to treat tuberculosis. This paper studied the antimycobacterial activity of 28 extracts from four different plant species that have been used in traditional Mexican medicine to treat tuberculosis. Bark and leaf crude extracts of <jats:italic>Juglans regia<\/jats:italic> L., <jats:italic>Juglans mollis<\/jats:italic> Engelm., <jats:italic>Carya illinoensis<\/jats:italic> (Wangenh) K. Koch and <jats:italic>Bocconia frutescens<\/jats:italic> showed <jats:italic>in vitro<\/jats:italic> anti\u2010<jats:italic>M. tuberculosis<\/jats:italic> activity. Hexane bark extracts from <jats:italic>C. illinoensis<\/jats:italic>, <jats:italic>J. mollis<\/jats:italic> and <jats:italic>J. regia<\/jats:italic> were the most active with a minimal inhibitory concentration (MIC) of 31, 50 and 100 \u00b5g\/mL, respectively. Ethanol bark extracts from <jats:italic>C. illinoensis<\/jats:italic> and <jats:italic>J. mollis<\/jats:italic> showed activity at 100 and 125 \u00b5g\/mL, respectively. Leaf extracts had the lowest activity. Methanol and hexane leaves extracts from B. frutescens had a MIC of 125 \u00b5g\/mL. None of the aqueous extracts showed antimycobacterial activity. Copyright \u00a9 2008 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.2343","type":"journal-article","created":{"date-parts":[[2008,3,13]],"date-time":"2008-03-13T17:53:20Z","timestamp":1205430800000},"page":"557-559","source":"Crossref","is-referenced-by-count":42,"title":["Antimycobacterial activity of Juglans regia, Juglans mollis, Carya illinoensis and Bocconia frutescens"],"prefix":"10.1002","volume":"22","author":[{"given":"Delia Elva","family":"Cruz\u2010Vega","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Julia","family":"Verde\u2010Star","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00e9","family":"Salinas\u2010Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bibiana","family":"Rosales\u2010Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris","family":"Estrada\u2010Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Mendez\u2010Arag\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Carranza\u2010Rosales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Teresa","family":"Gonz\u00e1lez\u2010Garza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Castro\u2010Garza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,3,13]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"Plantas Curativas del Noreste Mexicano","author":"Adame J","year":"2000"},{"key":"e_1_2_1_3_1","volume-title":"Herbario Medicinal del Instituto Mexicano del Seguro Social. 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