{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:11:12Z","timestamp":1792548672355,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,4,15]],"date-time":"2008-04-15T00:00:00Z","timestamp":1208217600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study was designed to evaluate the aphrodisiac and spermatogenic potential of the aqueous extract of dried roots of <jats:italic>Chlorophytum borivilianum<\/jats:italic> (CB) in rats. Male Wistar albino rats were divided into four groups. Rats were orally treated with (1) Control group: distilled water; (2) CB 125 mg\/kg\/day; (3) CB 250 mg\/kg\/day; and (4) Viagra<jats:sup>\u00ae<\/jats:sup> group: 4 mg\/kg\/day sildenafil citrate and their sexual behaviour was monitored 3 h later using a receptive female. Their sexual behaviour was evaluated on days 1, 7, 14, 21 and 28 of treatment by pairing with a pro\u2010oestrous female rat. For sperm count the treatment was continued further in all groups except the Viagra<jats:sup>\u00ae<\/jats:sup> group for 60 days. At 125 mg\/kg, CB had a marked aphrodisiac action, increased libido, sexual vigor and sexual arousal. Similarly, at the higher dose (250 mg\/kg) all the parameters of sexual behaviour were enhanced, but showed a saturation effect after day 14. On day 60 the sperm count increased significantly in both the CB groups, 125 mg\/kg and 250 mg\/kg, in a dose dependent manner. Thus, roots of <jats:italic>Chlorophytum borivilianum<\/jats:italic> can be useful in the treatment of certain forms of sexual inadequacies, such as premature ejaculation and oligospermia. Copyright \u00a9 2008 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.2369","type":"journal-article","created":{"date-parts":[[2008,4,15]],"date-time":"2008-04-15T17:52:04Z","timestamp":1208281924000},"page":"796-801","source":"Crossref","is-referenced-by-count":90,"title":["Effects of <i>Chlorophytum borivilianum<\/i> on sexual behaviour and sperm count in male rats"],"prefix":"10.1002","volume":"22","author":[{"given":"Rakesh","family":"Kenjale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riddhi","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadhana","family":"Sathaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,4,15]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"240","article-title":"Sexual behavior of male rats: effects of reduced sensory feedback","volume":"51","author":"Alder N","year":"1966","journal-title":"J Comp Physiol and Psychol"},{"key":"e_1_2_1_3_1","first-page":"321","article-title":"Aphrodisiac activity of the seeds of Mucuna pruriens","volume":"31","author":"Ananth Kumar KV","year":"1994","journal-title":"Indian Drugs"},{"key":"e_1_2_1_4_1","first-page":"60","article-title":"Male menopause","volume":"6","author":"Annuncio C","year":"2005","journal-title":"Outlook News Weekly"},{"key":"e_1_2_1_5_1","first-page":"15","volume-title":"Sarngadhar Samhita","author":"Ayurvedic Materia Medica:","year":"2001"},{"key":"e_1_2_1_6_1","first-page":"305","article-title":"Male infertility: risk factors in Mongolian men","volume":"6","author":"Bayasgalan G","year":"2004","journal-title":"Asian J Androl"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(87)80008-8"},{"key":"e_1_2_1_8_1","unstructured":"JM Davidson NJ Alexander 1978 Harper and Row New York 75 78"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1163\/156853967X00091"},{"key":"e_1_2_1_10_1","first-page":"448","volume-title":"The Rat in Laboratory Investigation","author":"Farris EJ","year":"1949"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02702958"},{"key":"e_1_2_1_12_1","volume-title":"Research in Human Reproduction","author":"Griffin PD","year":"1988"},{"key":"e_1_2_1_13_1","first-page":"67","article-title":"Herbal plants with aphrodisiac activity","volume":"42","author":"Indurwade NH","year":"2005","journal-title":"Indian Drugs"},{"key":"e_1_2_1_14_1","first-page":"12","article-title":"Aphrodisiac Indian herbs","volume":"2","author":"Jha NK","year":"2005","journal-title":"Phytopharm"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1258\/002367788780864547"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2005.08.012"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00567-1"},{"key":"e_1_2_1_18_1","first-page":"213","article-title":"Effects of Terminalia catappa seeds on sexual behaviour and fertility of male rats","volume":"2","author":"Ratnasooriya D","year":"2000","journal-title":"Asian J Androl"},{"key":"e_1_2_1_19_1","first-page":"175","article-title":"Herbal aphrodisiacs: a review","volume":"35","author":"Singh G","year":"1998","journal-title":"Indian Drugs"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-4-17"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-5-16"},{"key":"e_1_2_1_22_1","volume-title":"Product Monograph.","author":"Viagra\u00ae (Sildenafil citrate)","year":"2006"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fptr.2369","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.2369","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T01:36:53Z","timestamp":1700012213000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.2369"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,15]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["10.1002\/ptr.2369"],"URL":"https:\/\/doi.org\/10.1002\/ptr.2369","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,15]]}}}