{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:35:18Z","timestamp":1778661318174,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,12,23]],"date-time":"2010-12-23T00:00:00Z","timestamp":1293062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The methanol extract of ripe <jats:italic>Rumex crispus<\/jats:italic> L. fruits was evaluated for its antioxidant potential by assays for ferric\u2010reducing antioxidant power (FRAP), DPPH\u2010free radical scavenging activity (DPPH) and the influence on lipid peroxidation in liposomes (LP). Considerable activity was observed in all test systems (FRAP: 9.9 mmol Fe<jats:sup>2+<\/jats:sup>\/g; DPPH IC<jats:sub>50<\/jats:sub>: 3.7 \u03bcg\/mL; LP IC<jats:sub>50<\/jats:sub>: 4.9 \u03bcg\/mL), comparable to that of BHT (FRAP: 8.0 \u03bcg\/mL; DPPH IC<jats:sub>50<\/jats:sub>: 19.4 \u03bcg\/mL; LP IC<jats:sub>50<\/jats:sub>: 3.5 \u03bcg\/mL), but lower than the activity of ascorbic acid, rutin and quercetin, used as positive control substances. The <jats:italic>in vivo<\/jats:italic> effects were evaluated in several hepatic antioxidant systems (activities of LPx, GSH\u2010Px, Px, CAT and XOD, as well as GSH content), after treatment with the studied yellow dock extract in different doses, or in combination with carbon tetrachloride (CCl<jats:sub>4<\/jats:sub>). Pretreatment with the <jats:italic>R. crispus<\/jats:italic> extract inhibited CCl<jats:sub>4<\/jats:sub>\u2010induced oxidative stress by decreasing LPx and increasing GSH content in a dose dependent manner, bringing the levels of antioxidant enzymes to near control values. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.3234","type":"journal-article","created":{"date-parts":[[2010,7,8]],"date-time":"2010-07-08T03:13:56Z","timestamp":1278558836000},"page":"101-105","source":"Crossref","is-referenced-by-count":29,"title":["Antioxidant activity of yellow dock (<i>Rumex crispus<\/i> L., Polygonaceae) fruit extract"],"prefix":"10.1002","volume":"25","author":[{"given":"Zoran","family":"Maksimovi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nada","family":"Kova\u010devi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Branislava","family":"Laku\u0161i\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatjana","family":"\u0106ebovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,12,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0021-9258(19)50881-X","article-title":"Spectrophotometric method for measuring of breakdown of hydrogen peroxide by catalase","volume":"195","author":"Beers RFJ","year":"1950","journal-title":"J Biol Chem"},{"key":"e_1_2_6_3_1","first-page":"483","volume-title":"Methoden der enzymatischen Analyse","author":"Bergmayer UH.","year":"1970"},{"key":"e_1_2_6_4_1","first-page":"234","volume-title":"Red Cell Metabolism. A Manual of Biochemical Methods","author":"Beuthler E.","year":"1984"},{"key":"e_1_2_6_5_1","first-page":"882","article-title":"Improved methods for the determination of blood glutathione","volume":"61","author":"Beuthler E","year":"1983","journal-title":"J Lab Clin Med"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(99)00290-7"},{"key":"e_1_2_6_7_1","first-page":"306","volume-title":"Methods in Enzymology","author":"Buege AL","year":"1978"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.2464"},{"key":"e_1_2_6_9_1","first-page":"393","article-title":"The European mistletoe (Viscum album L.) grown on plums extract inhibits CCl4\u2010induced liver damage in rats","volume":"15","author":"\u0106ebovi\u0107 T","year":"2006","journal-title":"Fres Environ Bull"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hlca.19970800411"},{"key":"e_1_2_6_11_1","first-page":"223","volume-title":"Statistika za Istra\u017eiva\u010de u Oblasti Medicinskih Nauka","author":"Eri\u0107\u2010Marinkovi\u0107 J","year":"2006"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf9908188"},{"key":"e_1_2_6_13_1","first-page":"258","volume-title":"Methods of Enzymatic Analysis Volume III","author":"Goldberg DM","year":"1983"},{"key":"e_1_2_6_14_1","first-page":"259","volume-title":"A Modern Herbal","author":"Grieve M.","year":"1981"},{"key":"e_1_2_6_15_1","first-page":"232","volume-title":"Zlatna Knjiga Ljekovitog Bilja","author":"Gursky Z.","year":"1978"},{"key":"e_1_2_6_16_1","first-page":"1370","article-title":"Critical review on the determination of glutathione in biological preparations","volume":"33","author":"Higashi T.","year":"1988","journal-title":"Prot Nucleic Enz"},{"key":"e_1_2_6_17_1","first-page":"494","volume-title":"Medicinal Plants of SR Serbia","author":"Jan\u010di\u0107 R","year":"1989"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf030698a"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.9.2812"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/89.1.40"},{"key":"e_1_2_6_21_1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0015-3796(17)30073-2","article-title":"Study of metabolism enzymes during the development of Phaseous vulgaris","volume":"166","author":"Simon LM","year":"1974","journal-title":"Biochem Physiol Pflanz"},{"key":"e_1_2_6_22_1","first-page":"68","volume-title":"Flora of SR Serbia","author":"Slavni\u0107 \u017d","year":"1972"},{"key":"e_1_2_6_23_1","first-page":"684","volume-title":"Le\u010denje biljem","author":"Tucakov J.","year":"1997"},{"key":"e_1_2_6_24_1","first-page":"325","volume-title":"The Honest Herbal","author":"Tyler VE.","year":"1993"},{"key":"e_1_2_6_25_1","first-page":"32","volume-title":"Ishrana u Prirodi","author":"Vra\u010dari\u0107 B","year":"1977"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-00574-9"},{"key":"e_1_2_6_27_1","volume-title":"Practical Biochemistry for Colleges","author":"Wood EJ.","year":"1989"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf0103572"},{"key":"e_1_2_6_29_1","unstructured":"Yugoslav Pharmacopoeia2000.2001. Fifth Edition.Federal Institute for Health Protection and Promotion; Savremena administracija: Belgrade."}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fptr.3234","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.3234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T16:46:20Z","timestamp":1696783580000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.3234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,23]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1002\/ptr.3234"],"URL":"https:\/\/doi.org\/10.1002\/ptr.3234","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,23]]}}}