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Male Sprague\u2010Dawley rats were randomly divided into five groups and fed varying diets for an 8\u2010week period: control diet, HFD, and HFD supplemented with low, moderate or high doses of pu\u2010erh tea extract (0.5\u2009g, 2\u2009g and 4\u2009g\/kg BW\/day, respectively). Pu\u2010erh tea significantly reduced the total body weight and the weight of various adipose pads. Pu\u2010erh tea administration also significantly lowered plasma total cholesterol, triglyceride concentrations and low\u2010density lipoprotein\u2010cholesterol levels in rats with HFD\u2010induced obesity, but did not affect high\u2010density lipoprotein\u2010cholesterol levels. Moreover, pu\u2010erh tea significantly increased lipoprotein lipase, hepatic lipase and hormone\u2010sensitive lipase activities in epididymal fat tissue in rats with HFD\u2010induced obesity. Analysis of real\u2010time reverse transcription\u2010polymerase chain reaction results indicated that pu\u2010erh tea significantly enhanced mRNA levels of hormone\u2010sensitive lipase in rats with HFD\u2010induced obesity. These results suggest that pu\u2010erh tea attenuated visceral fat accumulation and improved hyperlipidemia in a rat model of HFD\u2010induced obesity. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.3247","type":"journal-article","created":{"date-parts":[[2010,7,16]],"date-time":"2010-07-16T13:50:17Z","timestamp":1279288217000},"page":"234-238","source":"Crossref","is-referenced-by-count":61,"title":["Effect of pu\u2010erh tea on body fat and lipid profiles in rats with diet\u2010induced 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