{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T17:09:29Z","timestamp":1772730569506,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This paper concerns the effects of methanol extract of <jats:italic>Eremostachys laciniata<\/jats:italic> on mild and moderate Carpal Tunnel Syndrome (CTS). Forty patients, including sixty hands affected by CTS, were randomly categorized in two different groups. Group A and Group B were treated with <jats:italic>E. laciniata<\/jats:italic> extract and placebo as the ointment, respectively. Tests, including the palmar prehension (pound), grip power (kg), visual analog scale (VAS) and electrodiagnostic study, were performed on all patients before and after the trial. During the trial, all patients receive Sodium Diclofenac (25\u2009mg twice a day) orally. In addition, they utilized a night wrist splint. After four weeks of treatment, the state of mean palmer prehension in both groups improved yet, the statistics show that group A prevailed by (<jats:italic>p<\/jats:italic>\u2009=\u20090.01). Grip power increased in both groups as well, but this increase was not significant within\u2010groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.18 and <jats:italic>p<\/jats:italic>\u2009=\u20090.54 in group A and B, respectively) or between\u2010groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.053). Although the VSA decreased in both groups, group A prevailed again by (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). After four weeks, no significant electrodiagnostic change was detected between the two groups. According to this study, the methanol extract of <jats:italic>E. laciniata<\/jats:italic> can be effective in treatment of mild and moderate CTS in combination with the wrist night splint, especially in alleviating the severity of the syndrome and increasing the palmer prehension power. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.3248","type":"journal-article","created":{"date-parts":[[2010,7,27]],"date-time":"2010-07-27T10:27:34Z","timestamp":1280226454000},"page":"290-295","source":"Crossref","is-referenced-by-count":18,"title":["Effect of <i>E. laciniata<\/i> (L) Ointment on Mild and Moderate Carpal Tunnel Syndrome: A Double\u2010blind, Randomized Clinical Trial"],"prefix":"10.1002","volume":"25","author":[{"given":"Bina","family":"Eftekharsadat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed","family":"Kazem Shakouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Shimia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Rahbar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morteza","family":"Ghojazadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Reza Rashidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Hadi Faraji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh571"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.2.153"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0004-9514(14)60152-5"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2006.00867.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.4.420-a"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-200203000-00005"},{"key":"e_1_2_6_8_1","first-page":"49","article-title":"Two bioactive ferulic acid derivatives from Eremostachys glabra","volume":"12","author":"Delazar A","year":"2004","journal-title":"DARU"},{"key":"e_1_2_6_9_1","first-page":"1","article-title":"Evaluation of analgesic activity of Eremostachys laciniata in mice","volume":"9","author":"Delazar A","year":"2009","journal-title":"J Nat Remed"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.1816"},{"key":"e_1_2_6_11_1","first-page":"731","article-title":"Ultrasound treatment for treating the carpal tunnel syndrome: randomised \u2018sham\u2019 controlled trial","volume":"7","author":"Gerold R","year":"1998","journal-title":"Br Med J"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.10.1245"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.60.8.813"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1360-8592(03)00068-8"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1105"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2006.04.004"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.2568"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ffj.1635"},{"key":"e_1_2_6_19_1","first-page":"33","article-title":"A comparison of the lidocaine patch 5% vs naproxen 500 mg twice daily for the relief of pain associated with carpal tunnel syndrome: a 6\u2010week, randomized, parallel\u2010group study","volume":"8","author":"Nalamachu S","year":"2006","journal-title":"Med Gen Med"},{"key":"e_1_2_6_20_1","first-page":"209","article-title":"Lidocaine patch 5% for carpal tunnel syndrome: how it compares with injections: a pilot study","volume":"55","author":"Nalamachu S","year":"2006","journal-title":"J Fam Pract"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1996.tb07077.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.11.1459"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269215507077294"},{"key":"e_1_2_6_24_1","first-page":"121","article-title":"Neutral wrist splinting in carpal tunnel syndrome: A 3 and 6 month clinical and neurophysiologic follow up evaluation of night\u2010only splint therapy","volume":"42","author":"Premoselli S","year":"2006","journal-title":"Eura Medicophys"},{"key":"e_1_2_6_25_1","first-page":"2122","article-title":"Using pyridoxine to treat carpal tunnel syndrome. 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