{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T13:20:16Z","timestamp":1769088016152,"version":"3.49.0"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,11,10]],"date-time":"2011-11-10T00:00:00Z","timestamp":1320883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Provincial Secretariat for Science and Technological Development of Vojvodina","award":["114-451-2056\/2011-01"],"award-info":[{"award-number":["114-451-2056\/2011-01"]}]},{"name":"The Ministry of Science and Technological Development, Republic of Serbia","award":["OI 172058"],"award-info":[{"award-number":["OI 172058"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>The appearance of common and self\u2010initiative usage of various herbal preparations in everyday practice and life imposes the question of possible interactions with drugs. This survey examined the influence of acute and chronic peppermint oil (PO \u2013<jats:italic>Mentha<\/jats:italic>\u2009\u00d7\u2009<jats:italic>piperita<\/jats:italic>L., Lamiaceae; prepared as emulsion for oral use) on pentobarbitone\u2010induced sleeping time, analgesic effect of codeine and impairment of motor coordination caused by midazolam in mice. The chemical profile of essential oil was determined by GC\u2010MS. Applied doses of PO were 0.1 and 0.2\u2009mL\/kg. Chronic PO intake (in both doses) led to significant decrease of analgesic effect of codeine, while acute intake of PO did not change this effect. Acute PO pretreatment in higher dose caused significant prolongation of pentobarbitone\u2010induced sleeping time, while it was significantly shortened by chronic PO pretreatment at the same dose. Midazolam effect was enhanced and prolonged significantly by chronic PO intake at higher dose, while acute intake of PO did not change this effect. Gut motility was increased only by acute intake of higher PO dose. Regarding the fact that PO produces changes in tested drug effects, the interaction between drugs and phytopreparations containing PO should be additionally followed\/confirmed in humans. Copyright \u00a9 2011 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.3638","type":"journal-article","created":{"date-parts":[[2011,11,10]],"date-time":"2011-11-10T11:38:49Z","timestamp":1320925129000},"page":"820-825","source":"Crossref","is-referenced-by-count":19,"title":["Acute and Chronic Pretreatment with Essential Oil of Peppermint (<i>Mentha<\/i>\u00d7<i>piperita<\/i>L., Lamiaceae) Influences Drug Effects"],"prefix":"10.1002","volume":"26","author":[{"given":"Isidora","family":"Samojlik","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Pharmacology, Toxicology and Clinical Pharmacology University of Novi Sad Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stojan","family":"Petkovi\u0107","sequence":"additional","affiliation":[{"name":"Centre for Forensic Medicine, Toxicology and Molecular Genetics Clinical Centre of Vojvodina Novi Sad Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda","family":"Mimica\u2010Duki\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Sciences, Department of Chemistry University of Novi Sad Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biljana","family":"Bo\u017ein","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pharmacy University of Novi Sad Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,11,10]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Identification of Essential Oil Components by Gas Chromatography\u2010Mass Spectroscopy","author":"Adams RP","year":"1995"},{"key":"e_1_2_6_3_1","volume-title":"The Complete German Commission E Monographs \u2010 Therapeutic Guide to Herbal Medicines","author":"Blumenthal M","year":"1998"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2010.04.001"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2004.03.005"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2002.126409"},{"key":"e_1_2_6_7_1","volume-title":"4th edition","author":"European Pharmacopeia","year":"2002"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-004-0847-8"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.1999.00780.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-7843.2008.00227.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200565090-00005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.2165\/11317010-000000000-00000"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2165\/01197065-200502040-00004"},{"key":"e_1_2_6_14_1","first-page":"154","article-title":"The effects of the genetic absence and inhibition of CYP2D6 on the metabolism of codeine and its derivatives, hydrocodone and oxycodone","volume":"45","author":"Lurcott G","year":"1999","journal-title":"Anesth Prog"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0090-9556(25)07052-7","article-title":"Studies on the metabolism of l\u2010menthol in rats","volume":"16","author":"Madyastha KM","year":"1988","journal-title":"Drug Metab Disposit"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.1936"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-39704"},{"key":"e_1_2_6_18_1","first-page":"243","article-title":"Composition and variation of essential oil constituents in three Mentha L. 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