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The use of the elevated plus\u2010maze test revealed that diazepam (2\u2009mg\/kg) or \u03b1\u2010asarone (3.5\u2009mg\/kg) increased the percentage of entries into open arms and of the time spent on open arms. In the light\/dark transition test, as with 2\u2009mg\/kg diazepam, 7\u2009mg\/kg \u03b1\u2010asarone increased the time spent in the light area and the number of transitions between the two compartments. In the novel food consumption test, \u03b1\u2010asarone (3.5, 7 and 14\u2009mg\/kg) caused significant increases in food intake during 5\u2009min as well as diazepam (0.5\u2009mg\/kg). In the marble burying test, \u03b1\u2010asarone also produced a significant inhibition of marble burying at doses of 14 and 28\u2009mg\/kg, as did diazepam (5\u2009mg\/kg). Thus, these findings indicated that \u03b1\u2010asarone exhibited an anxiolytic\u2010like effect. Further studies will be required to assess the generality of the present findings to other species and behavioral paradigms. Copyright \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.4596","type":"journal-article","created":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T06:52:37Z","timestamp":1328079157000},"page":"1476-1481","source":"Crossref","is-referenced-by-count":17,"title":["Anxiolytic\u2010like Effect of \u03b1\u2010Asarone in Mice"],"prefix":"10.1002","volume":"26","author":[{"given":"Shuang","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Pharmacology Shenyang Pharmaceutical University Box\u200941, 103 Wenhua Road 110016 Shenyang PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Shenyang Pharmaceutical University Box\u200941, 103 Wenhua Road 110016 Shenyang PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pharmacology 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