{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T20:38:47Z","timestamp":1789850327465,"version":"4.0.1"},"reference-count":60,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,1,9]],"date-time":"2015-01-09T00:00:00Z","timestamp":1420761600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>\n                    Three species of the genus\n                    <jats:italic>Trollius<\/jats:italic>\n                    (Ranunculaceae) are traditionally used to treat upper respiratory tract infections, pharyngitis, tonsillitis, bronchitis, cold with fever, acute tympanitis, aphthae, mouth sore, hemorrhage and pain of gums, acute lymphangitis and acute periostitis. However, only a few studies support its traditional use. These are studies of the biological activity of extracts and\/or compounds of selected species of\n                    <jats:italic>Trollius<\/jats:italic>\n                    , but there are no clinical studies proving the effectiveness or possible toxic effects. Until now, the following activity of extracts and\/or compounds from certain species of\n                    <jats:italic>Trollius<\/jats:italic>\n                    used in traditional medicine has been proven: antiviral, antibacterial, antiinflammatory and antioxidant. The review showed that flavonoids, mainly C\u2010glycosides, were characteristic of the species\n                    <jats:italic>Trollius.<\/jats:italic>\n                    Furthermore, other main groups of compounds are carotenoids, organic acids, terpenes, alkaloids, sterols, lactones and carbohydrates. The essential oil mainly contains compounds from the group of benzenoids, nitrogen\u2010containing compounds, monoterpenoids and sesquiterpenoids, irregular terpenes and macrocyclic epoxide. Copyright \u00a9 2015 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/ptr.5277","type":"journal-article","created":{"date-parts":[[2015,1,9]],"date-time":"2015-01-09T03:12:48Z","timestamp":1420773168000},"page":"475-500","source":"Crossref","is-referenced-by-count":22,"title":["The Genus\n                    <i>Trollius<\/i>\n                    \u2014Review of Pharmacological and Chemical Research"],"prefix":"10.1002","volume":"29","author":[{"given":"Ewa","family":"Witkowska\u2010Banaszczak","sequence":"first","affiliation":[{"name":"Department of Pharmacognosy Poznan University of Medical Sciences  Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,9]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"2565","article-title":"Antioxidant effects of the orientin and vitexin in Trollius chinensis Bunge in D\u2010galactose\u2010aged mice","volume":"7","author":"An F","year":"2012","journal-title":"Neural Regeneration Res"},{"key":"e_1_2_4_3_1","first-page":"1","article-title":"Struktura ekologiczna populacji pe\u0142nika europejskiego (Trollius europaeus L. subsp europaeus) w Polsce p\u00f3\u0142nocno \u2010 zachodniej","volume":"116","author":"Antkowiak W","year":"1999","journal-title":"Rocz Akad Rol Pozn"},{"key":"e_1_2_4_4_1","unstructured":"BrunetonJ.1999.Tonic plants dangerous to humans and animals. 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