{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:04:47Z","timestamp":1790417087665,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T00:00:00Z","timestamp":1426032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>One of the Brazilian arnicas, <jats:italic>Solidago chilensis<\/jats:italic> Meyen, is a species of the Asteraceae family. This plant is known by this common name because it shares remarkably similar organoleptic properties with the genus <jats:italic>Arnica<\/jats:italic> L., also within the family Asteraceae. We examined the effectiveness of the <jats:italic>S. chilensis<\/jats:italic> fluid extract used externally for treating tendinitis of flexor and extensor tendons of wrist and hand in placebo\u2010controlled double\u2010blind clinical pharmacological studies. This study was approved by the Ethical Committee for Scientific Research in Human Beings at University Vila Velha\u2010UVV. Two daily skin applications on the arm skin of a gel cream containing a 5% glycolic plant extract were administered to eight volunteers for 21\u2009days. Among the volunteers, one of their arms was used as the placebo group, and the other one was used as a test group. Statistical data analyses demonstrated a significant reduction in the perception of pain in the arms in the test group, when it was compared to those receiving only the placebo. Copyright \u00a9 2015 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.5323","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T11:35:29Z","timestamp":1426073729000},"page":"864-869","source":"Crossref","is-referenced-by-count":13,"title":["A Clinical Trial with Brazilian Arnica (<i>Solidago chilensis<\/i> Meyen) Glycolic Extract in the Treatment of Tendonitis of Flexor and Extensor Tendons of Wrist and Hand"],"prefix":"10.1002","volume":"29","author":[{"given":"Ary Gomes","family":"da Silva","sequence":"first","affiliation":[{"name":"Laboratory of Functional Ecology University of Vila Velha\u2014UVV  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elbe Rodrigues","family":"Machado","sequence":"additional","affiliation":[{"name":"Department of Pharmacy University of Vila Velha\u2014UVV\u2010ES  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo Mendes","family":"de 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