{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T19:32:45Z","timestamp":1772911965156,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytother. Res."],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1002\/ptr.5842","type":"journal-article","created":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T07:56:44Z","timestamp":1496303804000},"page":"1215-1219","source":"Crossref","is-referenced-by-count":21,"title":["Cytotoxic Properties of the Stem Bark of<i>Citrus reticulata<\/i>Blanco (Rutaceae)"],"prefix":"10.1002","volume":"31","author":[{"given":"Tasmia","family":"Tahsin","sequence":"first","affiliation":[{"name":"Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; James Parsons Building, Byrom Street Liverpool L3 3AF UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5111-4361","authenticated-orcid":false,"given":"Jean Duplex","family":"Wansi","sequence":"additional","affiliation":[{"name":"Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; James Parsons Building, Byrom Street Liverpool L3 3AF UK"},{"name":"Department of Chemistry; University of Douala, Faculty of Sciences; 24157 Douala Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afaf","family":"Al-Groshi","sequence":"additional","affiliation":[{"name":"Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; James Parsons Building, Byrom Street Liverpool L3 3AF UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Evans","sequence":"additional","affiliation":[{"name":"Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; James Parsons Building, Byrom Street Liverpool L3 3AF UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lutfun","family":"Nahar","sequence":"additional","affiliation":[{"name":"Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; James Parsons Building, Byrom Street Liverpool L3 3AF UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Martin","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Faculty of Science and Engineering; University of Wolverhampton; Wulfruna Street Wolverhampton WV1 1LY UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satyajit Dey","family":"Sarker","sequence":"additional","affiliation":[{"name":"Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences; Liverpool John Moores University; James Parsons Building, Byrom Street Liverpool L3 3AF UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,6,1]]},"reference":[{"key":"10.1002\/ptr.5842-BIB0001|ptr5842-cit-0002","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1094\/Phyto-78-1678","article-title":"Accumulation of scoparone, a phytoalexin associated with resistance of Citrus to Phytophthora citrophthora","volume":"78","author":"Afek","year":"1988","journal-title":"Phytopathology"},{"key":"10.1002\/ptr.5842-BIB0002|ptr5842-cit-0003","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3109\/13880209.2010.509734","article-title":"Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines","volume":"49","author":"Al-Ashaal","year":"2011","journal-title":"Pharm Biol"},{"key":"10.1002\/ptr.5842-BIB0003|ptr5842-cit-0004","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1002\/ptr.5329","article-title":"Comparative cytotoxicity of Glycyrrhiza glabra roots from different geographical origins against immortal human keratinocyte (HaCaT), lung adenocarcinoma (A549) and liver carcinoma (nG2) cells","volume":"29","author":"Basar","year":"2015","journal-title":"Phytother Res"},{"key":"10.1002\/ptr.5842-BIB0004|ptr5842-cit-0005","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.bmcl.2015.12.028","article-title":"Oxidative burst inhibition, cytotoxicity and antibacterial acriquinoline alkaloids from Citrus reticulata (Blanco)","volume":"26","author":"Fomani","year":"2016","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1002\/ptr.5842-BIB0005|ptr5842-cit-0006","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.jep.2011.03.048","article-title":"Typhonium blumei extract inhibits proliferation of human lung adenocarcinoma A549 cells via induction of cell cycle arrest and apoptosis","volume":"135","author":"Hsu","year":"2011","journal-title":"J Ethnopharmacol"},{"key":"10.1002\/ptr.5842-BIB0006|ptr5842-cit-0007","first-page":"1338","article-title":"Bioactive compounds and antioxidant capacities in different edible tissues of citrus fruit of four species","volume":"4","author":"Li","year":"2007","journal-title":"Food Chem"},{"issue":"11","key":"10.1002\/ptr.5842-BIB0007|ptr5842-cit-0008","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1515\/znb-2015-0083","article-title":"Cytotoxic 24-nor-ursane-typ triterpenoids from the twigs of Mostuea hirsuta","volume":"70","author":"Longue","year":"2015","journal-title":"Z Naturforsch"},{"key":"10.1002\/ptr.5842-BIB0008|ptr5842-cit-0009","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.3390\/molecules14051713","article-title":"Cytotoxic components of Pereskia bleo (Kunth) DC. (Cactaceae) leaves","volume":"14","author":"Malek","year":"2009","journal-title":"Molecules"},{"key":"10.1002\/ptr.5842-BIB0009|ptr5842-cit-0010","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.phymed.2008.09.001","article-title":"Citrus bioactive compounds improve bone quality and plasma antioxidant activity in orchidectomized rats","volume":"16","author":"Mandadi","year":"2009","journal-title":"Phytomedicine"},{"key":"10.1002\/ptr.5842-BIB0010|ptr5842-cit-0011","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J Immunol Methods"},{"key":"10.1002\/ptr.5842-BIB0011|ptr5842-cit-0012","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jcis.2015.07.005","article-title":"On the photocatalytic reduction of MTT tetrazolium salt on the surface of TiO 2 nanoparticles: formazan production kinetics and mechanism","volume":"457","author":"Popescu","year":"2015","journal-title":"J Colloid Interface Sci"},{"key":"10.1002\/ptr.5842-BIB0012|ptr5842-cit-0013","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1663\/0013-0001(2003)057[0502:TIOCCT]2.0.CO;2","article-title":"The introduction of cultivated citrus to Europe via northern Africa and the Iberian Peninsula","volume":"57","author":"Ram\u00f3n-Laca","year":"2003","journal-title":"Econ Bot"},{"key":"10.1002\/ptr.5842-BIB0013|ptr5842-cit-0014","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1016\/j.bmcl.2012.05.052","article-title":"Steroids from Commiphora mukul display antiproliferative effect against human prostate cancer PC3 cells via induction of apoptosis","volume":"22","author":"Shen","year":"2012","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1002\/ptr.5842-BIB0014|ptr5842-cit-0015","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1021\/np50066a017","article-title":"Xanthylytin and Xanthoxyletin from a Gorgonian, Echinogorgia sp","volume":"52","author":"Tillekeratne","year":"1989","journal-title":"J Nat Prod"},{"key":"10.1002\/ptr.5842-BIB0015|ptr5842-cit-0016","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1002\/mnfr.200800057","article-title":"Monodemethylated polymethoxyflavones from sweet orange (Citrus sinensis) peel inhibit growth of human lung cancer cells by apoptosis","volume":"53","author":"Xiao","year":"2009","journal-title":"Mol Nutr Food Res"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fptr.5842","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/ptr.5842","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T02:03:46Z","timestamp":1625364226000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.5842"}},"subtitle":["Cytotoxic property of stem bark of Citrus reticulata Blanco"],"short-title":[],"issued":{"date-parts":[[2017,6,1]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"URL":"https:\/\/doi.org\/10.1002\/ptr.5842","archive":["Portico"],"relation":{},"ISSN":["0951-418X"],"issn-type":[{"value":"0951-418X","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6,1]]}}}