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The main clinical manifestation of COVID\u201019 is the presence of respiratory symptoms, but some patients develop severe cardiovascular and renal complications. There is an urgency to understand the mechanism by which this virus causes complications so as to develop treatment options. Curcumin, a natural polyphenolic compound, could be a potential treatment option for patients with coronavirus disease. In this study, we review some of the potential effects of curcumin such as inhibiting the entry of virus to the cell, inhibiting encapsulation of the virus and viral protease, as well as modulating various cellular signaling pathways. This review provides a basis for further research and development of clinical applications of curcumin for the treatment of newly emerged SARS\u2010CoV\u20102.<\/jats:p>","DOI":"10.1002\/ptr.6738","type":"journal-article","created":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T01:28:06Z","timestamp":1589938086000},"page":"2911-2920","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":263,"title":["Potential effects of curcumin in the treatment of\n                    <scp>COVID<\/scp>\n                    \u201019 infection"],"prefix":"10.1002","volume":"34","author":[{"given":"Fatemeh","family":"Zahedipour","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnology, School of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyede Atefe","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Department of Medical 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