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The phytochemicals have been used in wide distribution of vector ailments such as malaria. The demand of the phytochemicals is based on the medicines which are mostly considered to be safer, less harmful than synthetic drugs and nontoxic. This review mentions majorly about the phytochemicals potentially inhibiting dengue fever around the world. The phytochemicals have been isolated from different species, have potential for the treatment of dengue. Different crude extracts and essential oils obtained from different species showed a broad activity against different phytochemicals. The current studies showed that natural products represent a rich source of medicines toward the dengue fever. Furthermore, ethnobotanical surveys and laboratory investigation established identified natural plants species in the development of drug discovery to control the dengue fever.<\/jats:p>","DOI":"10.1002\/ptr.6917","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T06:24:20Z","timestamp":1603952660000},"page":"1782-1816","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["A systematic review on phytochemicals for the treatment of dengue"],"prefix":"10.1002","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1438-4223","authenticated-orcid":false,"given":"Faraat","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Inspection and Licensing, Laboratory Services Botswana Medicines Regulatory Authority Gaborone Botswana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anushma","family":"Chorsiya","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Delhi Pharmaceutical Sciences and Research University New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varisha","family":"Anjum","sequence":"additional","affiliation":[{"name":"Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy Jamia Hamdard New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaik","family":"Khasimbi","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR) New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Chemical and Life Sciences Jamia Hamdard New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,28]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2221-1691(11)60055-5"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/np200715v"},{"issue":"2","key":"e_1_2_13_4_1","first-page":"34","article-title":"Mechanistic approach of drug discovery from natural substances for thrombocytopenia: A major cause of death in dengue fever patients","volume":"4","author":"Anjum V.","year":"2015","journal-title":"Annals of Phytomedicine"},{"key":"e_1_2_13_5_1","first-page":"1","volume-title":"Alkaloids","author":"Anonymous","year":"2015"},{"key":"e_1_2_13_6_1","unstructured":"Anonymous. 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