{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:13:03Z","timestamp":1792271583157,"version":"4.4.0"},"reference-count":196,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T00:00:00Z","timestamp":1752019200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Atherosclerosis is a chronic inflammatory disease and a major global health concern. In recent years, traditional Chinese medicines (TCMs) have demonstrated multi\u2010target therapeutic potential against atherosclerosis by modulating inflammatory responses, oxidative stress, lipid metabolism, and gut microbiota interactions. This review systematically evaluates (1) the anti\u2010atherogenic mechanisms of key TCM herbs (e.g.,\n                    <jats:italic>Panax ginseng<\/jats:italic>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Salvia miltiorrhiza<\/jats:italic>\n                    <\/jats:styled-content>\n                    ) and bioactive compounds (e.g., ginsenosides, tanshinones), (2) their synergistic effects in proprietary formulations, and (3) clinical evidence for cardiovascular protection. Notably, we highlight how TCM compounds like berberine and resveratrol target the gut\u2010vascular axis by regulating microbiota\u2010derived metabolites (e.g., TMAO) and improving endothelial function. While preclinical studies show promising results through Nrf2\/HO\u20101 activation, NF\u2010\u03baB inhibition, and plaque stabilization, translational challenges persist, including the lack of standardization and microbiome\u2010dependent efficacy variations. We conclude that integrating TCM's multi\u2010component advantages with cutting\u2010edge technologies such as bioinformatics, nanotechnology, and patient\u2010specific multiomics including microbiome profiling could revolutionize atherosclerosis management, though rigorous clinical validation and standardization remain imperative.\n                  <\/jats:p>","DOI":"10.1002\/ptr.70037","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T01:45:01Z","timestamp":1752111901000},"page":"3709-3735","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["An Up\u2010to\u2010Date Review of Traditional Chinese Medicine in the Treatment of Atherosclerosis: Components, Mechanisms, and Therapeutic Potentials"],"prefix":"10.1002","volume":"39","author":[{"given":"Dilaram","family":"Nijat","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences and Institute of Materia Medica Xinjiang University  Urumqi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingzhe","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Life Science and Technology, Xinjiang Key Laboratory of Biological Resources and Genetic Engineering Xinjiang University  Urumqi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulhasal","family":"Abdurixit","sequence":"additional","affiliation":[{"name":"Uygur Medical Hospital of Xinjiang Uygur Autonomous Region  Urumqi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"He","sequence":"additional","affiliation":[{"name":"College of Life Science and Technology, Xinjiang Key Laboratory of Biological Resources and Genetic Engineering Xinjiang University  Urumqi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4212-2503","authenticated-orcid":false,"given":"Haipeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Centre for Intelligent Healthcare, Coventry University  Coventry UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyao","family":"Li","sequence":"additional","affiliation":[{"name":"College of Life Science and Technology, Xinjiang Key Laboratory of Biological Resources and Genetic Engineering Xinjiang University  Urumqi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5599"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods10010045"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.112658"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105364"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.22088\/ijmcm.Bums.11.3.236"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110985"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11233843"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24213961"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11020232"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells12040522"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2021.07.057"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2020.109323"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods12030520"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2025.107742"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011\u2010023\u201004021\u20103"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph17040504"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11655\u2010009\u20100403\u20106"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14204334"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201059854\u20102"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.33533\/jpm.v17i1.5822"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00425\u2010017\u20102730\u20108"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569\u2010021\u201000668\u20104"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2019.105769"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.5114\/fn.2022.118184"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/1750\u20103841.15482"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.21037\/apm\u201022\u2010748"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008\u20100322"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27103292"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.154768"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1039\/d0fo01896a"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.14480"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201100741"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28114263"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2023.3689"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.120.000096"},{"issue":"8","key":"e_1_2_12_37_1","first-page":"6745","article-title":"Exploring the Anti\u2010Atherosclerosis Mechanism of Ginsenoside Rb1 by Integrating Network Pharmacology and Experimental Verification","volume":"16","author":"Hou L. J.","year":"2024","journal-title":"Aging"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.131701"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2017.06.012"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms13011258"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0303060"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sajb.2021.11.050"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2025.156775"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2015.10.023"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2016.06.004"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2022.116011"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu16071035"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/app11010386"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15020639"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hjc.2023.08.011"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2012.12.017"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods9040534"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201200704"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9020106"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2019.01.010"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.85204"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/1053617"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods12112120"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2009.76"},{"key":"e_1_2_12_60_1","article-title":"Effect of TanshinoneIIA on Inflammatory Response in Chinese Mini Swine With Coronary Atherosclerosis","volume":"64","author":"Li L.","year":"2016","journal-title":"Journal of the American Geriatrics Society"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2021.05.005"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2010.02.048"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.23569"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1039\/c9fo00396g"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.12360\/cpb202111097"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1159\/000438570"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.2095\u20101736.2016.06.094"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crfs.2024.100718"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5892306"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.4371"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22293"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.16333\/j.1001\u20106880.2020.4.015"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpp\/rgac102"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10753\u2010018\u20100807\u20106"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/iid3.1164"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7590"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11655\u2010023\u20103645\u20109"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.14356"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2020.11.021"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2023.22251"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5881321"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods12203852"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2014.06.024"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112098"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495\u2010017\u20101381\u20103"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2021.114799"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.14455"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1159\/000492257"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12081513"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2008.06.004"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2022.02.024"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.3109\/13880209.2014.948635"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods9030340"},{"key":"e_1_2_12_94_1","first-page":"71","volume-title":"Advances in Pharmacology","author":"Miao M.","year":"2020"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15051208"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjac.2025.100502"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.5830\/cvja\u20102011\u2010068"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.10.027"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2020.114246"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2023.114973"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2025.114459"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1409"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e26093"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9738745"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.805266"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1080\/08927022.2011.651138"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20204981"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2021.05.001"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.2174\/0118715230278980231212103709"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2022.11274"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.2174\/1566524022666211222161637"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25225474"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2023.2299305"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu15010224"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-57570-0_5"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl\u20102024\u2010325104"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c03100"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570161115666170713094319"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hermed.2022.100550"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2024.107236"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154561"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154408"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2018.04.038"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.08.148"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2025.1523553"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1081\/iph\u2010120014730"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11684\u2010019\u20100724\u20106"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11684\u2010018\u20100655\u20107"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2017.04.014"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41401\u2010018\u20100010\u20101"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.25548"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1836"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2017.03.004"},{"key":"e_1_2_12_134_1","first-page":"25","article-title":"Parthenolide Attenuates Atherosclerosis Progression via Autophagy Induction Through Caspase\u20101 Inhibition","volume":"42","author":"Sultan A. M.","year":"2023","journal-title":"Latin American Journal of Pharmacy"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.16438\/j.0513\u20104870.2013.04.015"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1921457"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28041845"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1111\/1440\u20101681.12412"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6485"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2025.1552117"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.07.038"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prostaglandins.2015.09.004"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.15267"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28041861"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155662"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1507420"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154220"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.111335"},{"issue":"8","key":"e_1_2_12_149_1","article-title":"Intervention Study of Combination Therapy Using Tongxinluo and Atorvastatin With Brain Ultrasounds on Carotid Vulnerable Plaque","volume":"12","author":"Wang H. J.","year":"2019","journal-title":"International Journal of Clinical and Experimental Medicine"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1039\/d3fo05747j"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113075"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749\u20108546\u20106\u201037"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8913926"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prmcm.2023.100267"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.90098"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201036614\u2010w"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7962"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.1161\/atvbaha.123.320065"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1161\/circresaha.118.313591"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2019.172717"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18102034"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.16865\/j.cnki.1000\u20107555.2014.07.002"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13492"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12012\u2010024\u201009828\u20107"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c10163"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1178188"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.11844\/cjcb.2020.08.0017"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12672\u2010023\u201000798\u2010w"},{"key":"e_1_2_12_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155390"},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol_00000086"},{"issue":"10","key":"e_1_2_12_171_1","first-page":"10052","article-title":"The Effect of Astragalus Polysaccharide on the Therapeutics of Diabetic Cardiomyopathy in Diabetic Rats and Its Mechanism","volume":"9","author":"Yang J. Y.","year":"2016","journal-title":"International Journal of Clinical and Experimental Pathology"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.118533"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1255069"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109094"},{"key":"e_1_2_12_175_1","doi-asserted-by":"publisher","DOI":"10.1515\/hc\u20102022\u20100161"},{"key":"e_1_2_12_176_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242316736"},{"key":"e_1_2_12_177_1","doi-asserted-by":"publisher","DOI":"10.1080\/08923973.2022.2112218"},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2022.114588"},{"key":"e_1_2_12_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2024.105915"},{"key":"e_1_2_12_180_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1005\u20109040(09)60011\u20108"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2016.11.003"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419\u2010022\u201005183\u2010z"},{"issue":"2","key":"e_1_2_12_183_1","first-page":"57","article-title":"Oxymatrine Attenuates Lipid Accumulation in HepG2 Cells by Inducing Autophagy","volume":"32","author":"Zhang P. U.","year":"2016","journal-title":"Diabetes\/Metabolism Research and Reviews"},{"key":"e_1_2_12_184_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886\u2010024\u201002049\u2010y"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1203713"},{"key":"e_1_2_12_186_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1991"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.2024.J079"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chmed.2018.03.013"},{"key":"e_1_2_12_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.106436"},{"key":"e_1_2_12_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcms.2023.11.003"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2012.793"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.10552"},{"key":"e_1_2_12_193_1","doi-asserted-by":"publisher","DOI":"10.16303\/j.cnki.1005\u20104545.2009.05.022"},{"key":"e_1_2_12_194_1","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/2014030"},{"key":"e_1_2_12_195_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.07.019"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974\u2010020\u20101705\u2010z"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062731"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.70037","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ptr.70037","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.70037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:12:29Z","timestamp":1772993549000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.70037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,9]]},"references-count":196,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/ptr.70037"],"URL":"https:\/\/doi.org\/10.1002\/ptr.70037","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,9]]},"assertion":[{"value":"2025-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}