{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T05:28:52Z","timestamp":1784957332613,"version":"3.55.0"},"reference-count":368,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Gastric cancer, the fifth most prevalent cancer globally, presents a significant challenge for effective treatment. Despite advancements, chemotherapy is often hindered by severe side effects and drug resistance, whereas targeted immunotherapy exhibits inconsistent efficacy. Amidst these challenges, plant secondary metabolites or phytochemicals have emerged as promising agents for the prevention and treatment of gastric cancer. The aim of this review is to perform a comprehensive evaluation of the gastric cancer preventive and therapeutic effects of various phytochemicals with an understanding of related mechanisms of action. A structured literature search was followed to collect preclinical and clinical data on the effects of phytochemicals in combating gastric cancer. Results have indicated that alkaloids, glycosides, polyphenols, sulfur\u2010containing compounds, and terpenoids inhibited gastric cancer cell proliferation in\u00a0vitro and suppressed gastric tumor growth in\u00a0vivo. These effects are driven by mechanisms such as alterations of pro\u2010apoptotic and anti\u2010apoptotic proteins, induction of cell cycle arrest, and promotion of apoptosis and autophagy. Additionally, alkaloids and terpenoids influence cancer progression through epigenetic modifications, such as alterations in DNA methylation and histone modifications, as well as through regulating inflammatory pathways, such as the nuclear factor\u2010\u03baB pathway. Moreover, glycosides, polyphenols, and sulfur\u2010containing compounds modulate critical signaling pathways related to cancer cell survival, proliferation, progression, and metastasis, including rat sarcoma\/mitogen\u2010activated protein kinase, wingless\u2010related integration site\/\u03b2\u2010catenin, and phosphoinositide 3\u2010kinase\/protein kinase B\/mammalian target of rapamycin signal transduction pathway. Despite promising preclinical results, further detailed studies, including clinical trials, are crucial to validate the clinical utility of phytochemicals in gastric cancer prevention and therapy.<\/jats:p>","DOI":"10.1002\/ptr.70202","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T08:45:02Z","timestamp":1769157902000},"page":"1354-1407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Oncopreventive and Oncotherapeutic Potential of Plant Secondary Metabolites Against Gastric Cancer: A Review"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3179-2920","authenticated-orcid":false,"given":"Subhadas","family":"Chatterjee","sequence":"first","affiliation":[{"name":"Department of Pharmacy Sanaka Educational Trust's Group of Institutions  Durgapur West Bengal India"},{"name":"School of Pharmacy, The Neotia University  Sarisha West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7327-1619","authenticated-orcid":false,"given":"Sankhadip","family":"Bose","sequence":"additional","affiliation":[{"name":"School of Pharmacy, The Neotia University  Sarisha West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8583-0078","authenticated-orcid":false,"given":"Satarupa","family":"Acharjee","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Technology NSHM Knowledge Campus  Kolkata West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0743-5766","authenticated-orcid":false,"given":"Anindita","family":"Kundu","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Techno India University  Kolkata West Bengal India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5942-8827","authenticated-orcid":false,"given":"Sharad Kumar","family":"Tripathi","sequence":"additional","affiliation":[{"name":"Department of Life Sciences Arni University  Tanda Himachal Pradesh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4352-1784","authenticated-orcid":false,"given":"Vicen\u00e7","family":"Ruiz de Porras","sequence":"additional","affiliation":[{"name":"CARE Program, Germans Trias i Pujol Research Institute  Badalona Spain"},{"name":"Badalona Applied Research Group in Oncology (B\u00b7ARGO), Catalan Institute of Oncology  Badalona Spain"},{"name":"GRET and Toxicology Unit, Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences University of Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8761-357X","authenticated-orcid":false,"given":"Shweta S.","family":"Zinzuwadia","sequence":"additional","affiliation":[{"name":"Department of Pharmacology College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine  Bradenton Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9159-960X","authenticated-orcid":false,"given":"Anupam","family":"Bishayee","sequence":"additional","affiliation":[{"name":"Department of Pharmacology College of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine  Bradenton Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1130562"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2020.05.011"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.14010"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7492"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115811"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29051093"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24108630"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2024.1438040"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/d1fo02120f"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6862"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573\u2010020\u201000114\u2010z"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612826666201125103941"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107706"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.129618"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.12935"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2021.108855"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1815"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155858"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.7386"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom14091166"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.27229"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-18657-8.00001-3"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.112727"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.8239"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032\u2010024\u201002459\u20106"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.2741\/3730"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.117977"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14091764"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29163784"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21969"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.16249"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2022.106118"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines11030554"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.710304"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210\u2010023\u201002645\u20109"},{"key":"e_1_2_8_37_1","first-page":"2895","article-title":"Phase I Clinical Trial of Curcumin, a Chemopreventive Agent, in Patients With High\u2010Risk or Pre\u2010Malignant Lesions","volume":"21","author":"Chen A. L.","year":"2001","journal-title":"Anticancer Research"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2014.2452"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13277\u2010014\u20102014\u2010x"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27185828"},{"key":"e_1_2_8_41_1","first-page":"997","article-title":"Effect of Isoverbascoside, a Phenylpropanoid Glycoside Antioxidant, on Proliferation and Differentiation of Human Gastric Cancer Cell","volume":"23","author":"Chen R.\u2010C.","year":"2002","journal-title":"Acta Pharmacologica Sinica"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2022.120950"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11030\u2010020\u201010101\u20106"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/09603271211064534"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12020461"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26062729"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13111653"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1177\/2058738419861600"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13277\u2010015\u20103178\u20108"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2009.02.022"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajco.13941"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2020.11.020"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16030585"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010017\u20101151\u20106"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2016.13"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.23278"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.37290\/ctnr2641\u2010452X.18:325\u2010330"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105666"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10068\u2010018\u20100337\u2010x"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756283X13501786"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13277\u2010016\u20104792\u20109"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1251895"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2021.1900060"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.202400063"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010024\u201012715\u20107"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555\u2010023\u201010161\u20108"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555\u2010023\u201010119\u2010w"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010024\u201012715\u20107"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231810713"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394\u2010021\u201002482\u20107"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2018.21"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.4129"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2014.599"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25010251"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_201901_16759"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i39.4389"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1080\/09637486.2018.1545012"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2021.153909"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo13030404"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.14231"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210\u2010024\u201003647\u2010x"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.101848"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010\u2010018\u20103329\u20105"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0000000000000491"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.16891"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228\u2010024\u201003764\u20109"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevOncog.2022045100"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12029\u2010017\u20109997\u20107"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22105406"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom9120839"},{"key":"e_1_2_8_91_1","first-page":"727","article-title":"PD\u20101\/PD\u2010L1 Pathway: Current Researches in Cancer","volume":"10","author":"Han Y.","year":"2020","journal-title":"American Journal of Cancer Research"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2019.37.4_suppl.129"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25147854"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25194553"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.21147\/j.issn.1000\u20109604.2022.03.04"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.28.574"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5237"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.117202"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2715"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2018.02.023"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2024.1382142"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26062558"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms15033432"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6647"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/fsn3.1872"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.08.012"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24010096"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2017.12.028"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13020\u2010023\u201000839\u20100"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00473"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26113301"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10149"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2015.2935"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210\u2010023\u201002550\u20101"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13194796"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.2174\/0113894501292466240627050638"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1177\/1934578X0800300727"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13184502"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2018.3532"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(17)31827\u20105"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.4103\/ghep.ghep_18_24"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.4103\/jcrt.JCRT_1017_20"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2017.12.005"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2019.08.014"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2023.0442"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2018.08.026"},{"key":"e_1_2_8_127_1","first-page":"1","article-title":"Activating Hippo Pathway via Rassf1 by Ursolic Acid Suppresses the Tumorigenesis of Gastric Cancer","volume":"20","author":"Kim S.","year":"2019","journal-title":"International Journal of Molecular Sciences"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17071155"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2020.108413"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222413455"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419\u2010018\u20100930\u20101"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18122589"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10719\u2010025\u201010180\u20103"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210\u2010023\u201002471\u2010z"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.11.040"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2020.00357"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552\u2010008\u20109132\u2010y"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10061350"},{"key":"e_1_2_8_139_1","first-page":"957","article-title":"Deguelin Promotes Apoptosis and Inhibits Angiogenesis of Gastric Cancer","volume":"24","author":"Lee H.","year":"2010","journal-title":"Oncology Reports"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2015.3982"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.33.931"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2008.0237"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116862"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2017.09.011"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2017.02.008"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534735417696702"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2014.3447"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2474805"},{"key":"e_1_2_8_149_1","first-page":"42","article-title":"Proapoptotic and Growth\u2010Inhibitory Effects of Plumbagin on Human Gastric Cancer Cells via Suppression of Signal Transducer and Activator of Transcription 3 and Protein Kinase B","volume":"23","author":"Li J.","year":"2017","journal-title":"Alternative Therapies in Health and Medicine"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2011.152"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/6195050"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113476"},{"key":"e_1_2_8_153_1","first-page":"1148","article-title":"Silibinin Promotes the Apoptosis of Gastric Cancer BGC823 Cells Through Caspase Pathway","volume":"22","author":"Li R.","year":"2017","journal-title":"Journal of Buon"},{"key":"e_1_2_8_154_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l5016"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2013.2717"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272\u2010016\u20100761\u20105"},{"key":"e_1_2_8_157_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323001103900610"},{"key":"e_1_2_8_158_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.1078090"},{"key":"e_1_2_8_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.06.006"},{"key":"e_1_2_8_160_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11123023"},{"key":"e_1_2_8_161_1","doi-asserted-by":"publisher","DOI":"10.2174\/0115680266282360240222062032"},{"key":"e_1_2_8_162_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28237897"},{"key":"e_1_2_8_163_1","first-page":"223","article-title":"Berberine Induced Down\u2010Regulation of Matrix Metalloproteinase\u20101, \u22122 and \u22129 in Human Gastric Cancer Cells (SNU\u20105) In\u00a0Vitro","volume":"22","author":"Lin J.\u2010P.","year":"2008","journal-title":"In Vivo"},{"key":"e_1_2_8_164_1","doi-asserted-by":"publisher","DOI":"10.4314\/tjpr.v20i12.13"},{"key":"e_1_2_8_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105935"},{"key":"e_1_2_8_166_1","first-page":"171","article-title":"A Randomized Study of Chemotherapy Versus Biochemistry With Chemotherapy Plus Aloe arborescens in Patients With Metastatic Cancer","volume":"23","author":"Lissoni P.","year":"2009","journal-title":"In Vivo"},{"key":"e_1_2_8_167_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.22723"},{"key":"e_1_2_8_168_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.89986"},{"key":"e_1_2_8_169_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10020\u2010024\u201000842\u20107"},{"key":"e_1_2_8_170_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8315"},{"key":"e_1_2_8_171_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2017.5648"},{"key":"e_1_2_8_172_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2013.810290"},{"key":"e_1_2_8_173_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115132"},{"key":"e_1_2_8_174_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010015\u20100398\u2010z"},{"key":"e_1_2_8_175_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.7080"},{"key":"e_1_2_8_176_1","first-page":"142","article-title":"Inhibitory Effects of Luteolin on Human Gastric Carcinoma Xenografts in Nude Mice and Its Mechanism","volume":"93","author":"Lu X.","year":"2013","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"e_1_2_8_177_1","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.13339"},{"key":"e_1_2_8_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2006.10.020"},{"key":"e_1_2_8_179_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12033\u2010023\u201000978\u20107"},{"key":"e_1_2_8_180_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906\u2010016\u20101360\u20101"},{"key":"e_1_2_8_181_1","first-page":"2000","article-title":"Antiproliferative Activity of Plumbagin (5\u2010Hydroxy\u20102\u2010Methyl\u20101, 4\u2010Naphthoquinone) in Human Gastric Carcinoma Cells Is Facilitated via Activation of Autophagic Pathway, Mitochondrial\u2010Mediated Programmed Cell Death and Inhibition of Cell Migration and Invasi","volume":"24","author":"Ma X.","year":"2019","journal-title":"Journal of Balkan Union of Oncology"},{"key":"e_1_2_8_182_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02307081"},{"key":"e_1_2_8_183_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15122768"},{"key":"e_1_2_8_184_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/79.5.727"},{"key":"e_1_2_8_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2024.122943"},{"key":"e_1_2_8_186_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476\u20104598\u201010\u2010107"},{"key":"e_1_2_8_187_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21020570"},{"key":"e_1_2_8_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hermed.2020.100375"},{"key":"e_1_2_8_189_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40661\u2010016\u20100024\u20107"},{"key":"e_1_2_8_190_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25173804"},{"key":"e_1_2_8_191_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210\u2010023\u201002673\u20105"},{"key":"e_1_2_8_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105837"},{"key":"e_1_2_8_193_1","doi-asserted-by":"publisher","DOI":"10.1080\/10496475.2020.1748784"},{"key":"e_1_2_8_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101404"},{"key":"e_1_2_8_195_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15072128"},{"key":"e_1_2_8_196_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.13548"},{"key":"e_1_2_8_197_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557520666200709175138"},{"key":"e_1_2_8_198_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(99)01048\u2010x"},{"key":"e_1_2_8_199_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25105569"},{"key":"e_1_2_8_200_1","doi-asserted-by":"publisher","DOI":"10.2174\/1574892817666220606104712"},{"key":"e_1_2_8_201_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b01285"},{"key":"e_1_2_8_202_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29174193"},{"key":"e_1_2_8_203_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2024.1380194"},{"key":"e_1_2_8_204_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11050611"},{"key":"e_1_2_8_205_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i7.1635"},{"key":"e_1_2_8_206_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032\u2010023\u201002211\u20106"},{"key":"e_1_2_8_207_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12732"},{"key":"e_1_2_8_208_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_8_209_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10565\u2010022\u201009772\u20108"},{"key":"e_1_2_8_210_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00204\u2010024\u201003861\u20109"},{"key":"e_1_2_8_211_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2015.1085581"},{"key":"e_1_2_8_212_1","doi-asserted-by":"publisher","DOI":"10.37349\/etat.2021.00049"},{"key":"e_1_2_8_213_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2018.9244"},{"key":"e_1_2_8_214_1","doi-asserted-by":"publisher","DOI":"10.1007\/s101200200042"},{"key":"e_1_2_8_215_1","first-page":"457","article-title":"Matrine Suppresses Proliferation and Invasion of SGC7901 Cells Through Inactivation of PI3K\/Akt\/uPA Pathway","volume":"46","author":"Peng X.","year":"2016","journal-title":"Annals of Clinical and Laboratory Science"},{"key":"e_1_2_8_216_1","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2022.019"},{"key":"e_1_2_8_217_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116251"},{"key":"e_1_2_8_218_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.27183"},{"key":"e_1_2_8_219_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X21500245"},{"key":"e_1_2_8_220_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0076486"},{"key":"e_1_2_8_221_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.613458"},{"key":"e_1_2_8_222_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27249009"},{"key":"e_1_2_8_223_1","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.931.252"},{"key":"e_1_2_8_224_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155902"},{"key":"e_1_2_8_225_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28145587"},{"key":"e_1_2_8_226_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2012.1694"},{"key":"e_1_2_8_227_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26237368"},{"key":"e_1_2_8_228_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026621666211105094939"},{"key":"e_1_2_8_229_1","doi-asserted-by":"publisher","DOI":"10.5114\/pg.2018.80001"},{"key":"e_1_2_8_230_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1349745"},{"key":"e_1_2_8_231_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2020.7708"},{"key":"e_1_2_8_232_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935\u2010023\u201003031\u20104"},{"key":"e_1_2_8_233_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.28587"},{"key":"e_1_2_8_234_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557520666201116144421"},{"key":"e_1_2_8_235_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2020.09.004"},{"key":"e_1_2_8_236_1","doi-asserted-by":"publisher","DOI":"10.1002\/mc.22512"},{"key":"e_1_2_8_237_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12010\u2010022\u201004099\u2010w"},{"key":"e_1_2_8_238_1","doi-asserted-by":"publisher","DOI":"10.1080\/02648725.2022.2162257"},{"key":"e_1_2_8_239_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5359.39365"},{"key":"e_1_2_8_240_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304\u2010018\u20100527\u20103"},{"key":"e_1_2_8_241_1","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22623"},{"key":"e_1_2_8_242_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/3268136"},{"key":"e_1_2_8_243_1","doi-asserted-by":"publisher","DOI":"10.33263\/BRIAC111.85028537"},{"key":"e_1_2_8_244_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010024\u201005656\u2010z"},{"key":"e_1_2_8_245_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13765\u2010022\u201000759\u2010x"},{"key":"e_1_2_8_246_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10010036"},{"key":"e_1_2_8_247_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.31303"},{"key":"e_1_2_8_248_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21871"},{"key":"e_1_2_8_249_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5483"},{"key":"e_1_2_8_250_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787\u2010024\u201001596\u20108"},{"key":"e_1_2_8_251_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874467215666220705142954"},{"key":"e_1_2_8_252_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/3456264"},{"key":"e_1_2_8_253_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16091711"},{"key":"e_1_2_8_254_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/915380"},{"key":"e_1_2_8_255_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5091"},{"key":"e_1_2_8_256_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2014.3662"},{"key":"e_1_2_8_257_1","doi-asserted-by":"publisher","DOI":"10.4314\/ajtcam.v10i6.5"},{"key":"e_1_2_8_258_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2005.06.026"},{"key":"e_1_2_8_259_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2019.152968"},{"key":"e_1_2_8_260_1","doi-asserted-by":"publisher","DOI":"10.1089\/cbr.2019.2874"},{"key":"e_1_2_8_261_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112152\u201020220120\u201000049"},{"key":"e_1_2_8_262_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2022.977374"},{"key":"e_1_2_8_263_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_8_264_1","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.202300768"},{"key":"e_1_2_8_265_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29061373"},{"key":"e_1_2_8_266_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29061320"},{"key":"e_1_2_8_267_1","doi-asserted-by":"publisher","DOI":"10.1615\/JEnvironPatholToxicolOncol.2022044317"},{"key":"e_1_2_8_268_1","doi-asserted-by":"publisher","DOI":"10.4314\/ajtcam.v11i1.28"},{"key":"e_1_2_8_269_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2018.09.022"},{"key":"e_1_2_8_270_1","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097\u20100215(19990129)80:3<396::aid\u2010ijc10>3.0.co;2\u20101"},{"key":"e_1_2_8_271_1","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.795"},{"key":"e_1_2_8_272_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00012339"},{"key":"e_1_2_8_273_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2019.01.031"},{"key":"e_1_2_8_274_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/2543504"},{"key":"e_1_2_8_275_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2015.00157"},{"key":"e_1_2_8_276_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033\u2010024\u201009978\u20105"},{"key":"e_1_2_8_277_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.104772"},{"key":"e_1_2_8_278_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S366630"},{"key":"e_1_2_8_279_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2021.109699"},{"key":"e_1_2_8_280_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105487"},{"key":"e_1_2_8_281_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01336"},{"key":"e_1_2_8_282_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e33342"},{"key":"e_1_2_8_283_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3997190"},{"key":"e_1_2_8_284_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13010115"},{"key":"e_1_2_8_285_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2023.107032"},{"key":"e_1_2_8_286_1","doi-asserted-by":"publisher","DOI":"10.1002\/kjm2.12322"},{"key":"e_1_2_8_287_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00473"},{"key":"e_1_2_8_288_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/419343"},{"key":"e_1_2_8_289_1","doi-asserted-by":"publisher","DOI":"10.7314\/apjcp.2014.15.16.6791"},{"key":"e_1_2_8_290_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201081815\u20102"},{"key":"e_1_2_8_291_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/180839"},{"key":"e_1_2_8_292_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.115031"},{"key":"e_1_2_8_293_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29163886"},{"key":"e_1_2_8_294_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2015.2383"},{"key":"e_1_2_8_295_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2021.734334"},{"key":"e_1_2_8_296_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.2134"},{"key":"e_1_2_8_297_1","doi-asserted-by":"publisher","DOI":"10.7785\/tcrt.2012.500434"},{"key":"e_1_2_8_298_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i29.4461"},{"key":"e_1_2_8_299_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010\u2010014\u20102214\u20100"},{"key":"e_1_2_8_300_1","doi-asserted-by":"publisher","DOI":"10.3727\/096504015X14410238486685"},{"key":"e_1_2_8_301_1","doi-asserted-by":"publisher","DOI":"10.51847\/oQ9XftWaCj"},{"key":"e_1_2_8_302_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2016.3670"},{"key":"e_1_2_8_303_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2020.108314"},{"key":"e_1_2_8_304_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0193449"},{"key":"e_1_2_8_305_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201100652"},{"key":"e_1_2_8_306_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2018.8388"},{"key":"e_1_2_8_307_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2014.3669"},{"key":"e_1_2_8_308_1","doi-asserted-by":"publisher","DOI":"10.1080\/09637486.2016.1198892"},{"key":"e_1_2_8_309_1","doi-asserted-by":"publisher","DOI":"10.21037\/tcr.2019.12.03"},{"key":"e_1_2_8_310_1","doi-asserted-by":"publisher","DOI":"10.11817\/j.issn.1672\u20107347.2017.10.001"},{"key":"e_1_2_8_311_1","doi-asserted-by":"publisher","DOI":"10.3390\/cimb44090298"},{"key":"e_1_2_8_312_1","first-page":"2135","article-title":"Phenethyl Isothiocyanate Inhibits Migration and Invasion of Human Gastric Cancer AGS Cells Through Suppressing MAPK and NF\u2010\u03baB Signal Pathways","volume":"30","author":"Yang M.\u2010D.","year":"2010","journal-title":"Anticancer Research"},{"key":"e_1_2_8_313_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0070627"},{"key":"e_1_2_8_314_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5570831"},{"key":"e_1_2_8_315_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.945627"},{"key":"e_1_2_8_316_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2017.06.001"},{"key":"e_1_2_8_317_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01392"},{"key":"e_1_2_8_318_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2018.7142"},{"key":"e_1_2_8_319_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11081481"},{"key":"e_1_2_8_320_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2016.06.018"},{"key":"e_1_2_8_321_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.56833"},{"key":"e_1_2_8_322_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2015.3008"},{"key":"e_1_2_8_323_1","first-page":"97","article-title":"Trends in Cancer Incidence in Esophagus, Stomach, Colon, Rectum and Liver in Males in India","volume":"9","author":"Yeole B. B.","year":"2008","journal-title":"Asian Pacific Journal of Cancer Prevention"},{"key":"e_1_2_8_324_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13577\u2010020\u201000339\u20105"},{"key":"e_1_2_8_325_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756\u20109966\u201031\u201046"},{"key":"e_1_2_8_326_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/518301"},{"key":"e_1_2_8_327_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2013.2893"},{"key":"e_1_2_8_328_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.155045"},{"key":"e_1_2_8_329_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2016.4696"},{"key":"e_1_2_8_330_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.114986"},{"key":"e_1_2_8_331_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11434\u2010007\u20100342\u20106"},{"key":"e_1_2_8_332_1","first-page":"1585","article-title":"Tumor Effects of \u03b2\u2010Carboline Alkaloids on SGC\u20107901 Tumor Bearing Mice Through FAK\/PI3K\/Akt\/mTOR Pathway","volume":"26","author":"Yuxiang F.","year":"2020","journal-title":"Herbei Medicina"},{"key":"e_1_2_8_333_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557520666200709175948"},{"key":"e_1_2_8_334_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2017.06.140"},{"key":"e_1_2_8_335_1","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2018.1493610"},{"key":"e_1_2_8_336_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13063"},{"key":"e_1_2_8_337_1","first-page":"1","article-title":"Lanatoside C Decelerates Proliferation and Induces Apoptosis Through Inhibition of STAT3 and ROS\u2010Mediated Mitochondrial Membrane Potential Transformation in Cholangiocarcinoma","volume":"14","author":"Zhang C.","year":"2023","journal-title":"Frontiers in Pharmacology"},{"key":"e_1_2_8_338_1","doi-asserted-by":"publisher","DOI":"10.4236\/oalib.1105217"},{"key":"e_1_2_8_339_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2012.11.034"},{"key":"e_1_2_8_340_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2013.09.007"},{"key":"e_1_2_8_341_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13277\u2010013\u20101193\u20101"},{"key":"e_1_2_8_342_1","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2013.15"},{"key":"e_1_2_8_343_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272\u2010020\u201001283\u20106"},{"key":"e_1_2_8_344_1","first-page":"71","article-title":"Radiosensitization Effect of Luteolin on Human Gastric Cancer SGC\u20107901 Cells","volume":"23","author":"Zhang Q.","year":"2009","journal-title":"Journal of Biological Regulators and Homeostatic Agents"},{"key":"e_1_2_8_345_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110245"},{"key":"e_1_2_8_346_1","doi-asserted-by":"publisher","DOI":"10.3892\/or_00001021"},{"key":"e_1_2_8_347_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2022.115300"},{"key":"e_1_2_8_348_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2018.9318"},{"key":"e_1_2_8_349_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2014.3109"},{"key":"e_1_2_8_350_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.4733"},{"key":"e_1_2_8_351_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.27491"},{"key":"e_1_2_8_352_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2018.6361"},{"key":"e_1_2_8_353_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11071349"},{"key":"e_1_2_8_354_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2020.12345"},{"key":"e_1_2_8_355_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154608"},{"key":"e_1_2_8_356_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2016.01.012"},{"key":"e_1_2_8_357_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2020.165856"},{"key":"e_1_2_8_358_1","doi-asserted-by":"publisher","DOI":"10.4103\/apjtb.apjtb"},{"key":"e_1_2_8_359_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2014.07.013"},{"key":"e_1_2_8_360_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40001\u2010023\u201001271\u20108"},{"key":"e_1_2_8_361_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v10.i12.1822"},{"key":"e_1_2_8_362_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.627"},{"key":"e_1_2_8_363_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906\u2010019\u20102779\u2010y"},{"key":"e_1_2_8_364_1","doi-asserted-by":"publisher","DOI":"10.3727\/096504015X14452563486011"},{"key":"e_1_2_8_365_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i18.2315"},{"key":"e_1_2_8_366_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2017.06.107"},{"key":"e_1_2_8_367_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22094763"},{"key":"e_1_2_8_368_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo13101081"},{"key":"e_1_2_8_369_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2016.02.058"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.70202","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ptr.70202","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.70202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:05:39Z","timestamp":1773029139000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.70202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,23]]},"references-count":368,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/ptr.70202"],"URL":"https:\/\/doi.org\/10.1002\/ptr.70202","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,23]]},"assertion":[{"value":"2025-05-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}