{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:49:48Z","timestamp":1788536988557,"version":"build-2803163510"},"reference-count":203,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:00:00Z","timestamp":1776729600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170567"],"award-info":[{"award-number":["82170567"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82300641"],"award-info":[{"award-number":["82300641"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Inflammatory bowel disease (IBD) is a group of chronic gastrointestinal inflammatory disorders, primarily including ulcerative colitis (UC) and Crohn's disease (CD). Reactive oxygen species (ROS) play a pivotal role in the pathogenesis of these diseases. Current treatments for IBD including aminosalicylates, corticosteroids, and immunosuppressive agents aim to alleviate symptoms or delay disease progression. However, long\u2010term use of these drugs may lead to certain toxic side effects, negatively affecting the patient's quality of life. Recent studies have highlighted the potential of various phytochemicals in modulating oxidative stress, inhibiting inflammatory responses, and protecting the intestinal barrier function. These phytochemicals alleviate oxidative stress in the gut by reducing ROS levels, suppressing the production of pro\u2010inflammatory cytokines, and enhancing the integrity of the intestinal barrier, thus improving IBD symptoms. This review summarizes the phytochemicals known to effectively alleviate gut oxidative stress and improve IBD, discusses their mechanisms of action, and emphasizes the promising future applications in the treatment of IBD.<\/jats:p>","DOI":"10.1002\/ptr.70339","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T02:45:31Z","timestamp":1776825931000},"page":"4005-4040","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Phytochemicals in Inflammatory Bowel Disease: Targeting Oxidative Stress for Improved Gut Health"],"prefix":"10.1002","volume":"40","author":[{"given":"Junyan","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixuan","family":"He","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Naval Medical University  Shanghai China"},{"name":"Changhai Clinical Research Unit Changhai Hospital, Naval Medical University  Shanghai China"},{"name":"National Key Laboratory of Immunity and Inflammation Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhao","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The Second Affiliated Hospital of Zhejiang University School of Medicine  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingnan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoshen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Naval Medical University  Shanghai China"},{"name":"Changhai Clinical Research Unit Changhai Hospital, Naval Medical University  Shanghai China"},{"name":"National Key Laboratory of Immunity and Inflammation Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The Third Xiangya Hospital, Central South University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Changhai Hospital, Naval Medical University  Shanghai China"},{"name":"Changhai Clinical Research Unit Changhai Hospital, Naval Medical University  Shanghai China"},{"name":"National Key Laboratory of Immunity and Inflammation Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/08923973.2014.998368"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0960327117751235"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.01.168"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2011.03.017"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.22514"},{"key":"e_1_2_12_7_1","first-page":"1015","article-title":"Substance P Promotes the Recovery of Oxidative Stress\u2010Damaged Retinal Pigmented Epithelial Cells by Modulating Akt\/GSK\u20103 Beta Signaling","volume":"22","author":"Baek S. M.","year":"2016","journal-title":"Molecular Vision"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2023.123253"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00044.2005"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trim.2024.101986"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00040.2012"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113020"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2020.06.006"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1113356"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3598"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2012.00239"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2006.11.006"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2021.06.025"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2002697"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28166070"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241310828"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01910"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2023.123496"},{"issue":"2","key":"e_1_2_12_24_1","first-page":"301","article-title":"Genkwanin Alleviates Mitochondrial Dysfunction and Oxidative Stress in a Murine Model of Experimental Colitis: The Participation of Sirt1","volume":"52","author":"Chen Z.","year":"2022","journal-title":"Annals of Clinical and Laboratory Science"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113335"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/1028415X.2018.1521088"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2019.158597"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064\u2010014\u20101377\u20100"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2016.06.023"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2013.06.007"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.688812"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.118025"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155653"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102004\u2010818942"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2020.109089"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2015.12.005"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.01.001"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.2001.281.3.G848"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c09215"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c05732"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1039\/c5fo01228g"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2017.06.003"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5706152"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2023.175745"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.24.17.7806\u20107819.2004"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6769789"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1139\/bcb\u20102018\u20100041"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787\u2010022\u201001074\u2010z"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787\u2010023\u201001277\u2010y"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787\u2010023\u201001387\u20107"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.03.038"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2023.09.019"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2013.06.003"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2018.09.004"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2020.109315"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1024\/0300\u20109831\/a000280"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.6.2886"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951\u2010023\u201001976\u20102"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.08.008"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2018.03.020"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2019.12.001"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201600976R"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010physiol\u2010060821\u2010083306"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/8343052"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2019.1570913"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2010.10.703"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0391102"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12333"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5871431"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.26.840"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.3906\/sag\u20101508\u201098"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319\u20103767.54750"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.31.7.786"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2019.108933"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008\u20105472.CAN\u201006\u20103562"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12101886"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.12.8116"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrfmmm.2009.09.007"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgr.2023.01.004"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules15107208"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.05.002"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25063210"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2015.02.019"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1635384"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i14.2483"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620\u2010017\u20104609\u20108"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/372739a0"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2023.154899"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c07474"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2016.08.020"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.111972"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202303016"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23147694"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210\u2010020\u201001814\u20104"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155941"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.31.1343"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2009.06.016"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1132"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25126613"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715760500197177"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/35008115"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nutres.2019.03.005"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2025.1494351"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2007.09.004"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19061668"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.23.13675"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2024.1390351"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836\u2010200006000\u201000006"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836\u2010199206001\u201000023"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(17)32448\u20100"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2014.0225"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101674"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1185"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10992"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2007.01.001"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000230"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c09901"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbae122"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1267"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S86345"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2013.01.004"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1200111"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105243"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.8614.1"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.4149\/gpb_2021044"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c17827"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535\u2010003\u20101336\u2010z"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.577237"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym9040137"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(80)91934\u20100"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2009.10.011"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2011.06.043"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.3164\/jcbn.18\u201047"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2016.07.003"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00327"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00025.2007"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27134139"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10753\u2010020\u201001218\u20109"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2022.132531"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201601013"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.08.006"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2013.11.019"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.3.307"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5271"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.19.11427"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2022.867318"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0901196"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24091801"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2022.100246"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1039\/d1fo03376j"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2018.01.002"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27103093"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326\u20105377.2006.tb00548.x"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.3c02007"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155378"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394\u2010014\u20100745\u20105"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0705241"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_201812_16652"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5528"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9121211"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2021.112123"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2021.1948066"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2021.153804"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010\u2010017\u20103208\u20105"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c06755"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11061212"},{"key":"e_1_2_12_167_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010011\u20101352\u2010z"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2021.111756"},{"key":"e_1_2_12_169_1","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20182297"},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2013.09.001"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja17.01001"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2023.2168249"},{"key":"e_1_2_12_173_1","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X18500660"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092\u20108674(00)80611\u2010X"},{"key":"e_1_2_12_175_1","doi-asserted-by":"publisher","DOI":"10.1039\/d1fo03888e"},{"key":"e_1_2_12_176_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00512.2009"},{"key":"e_1_2_12_177_1","doi-asserted-by":"publisher","DOI":"10.1021\/np4006772"},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S210315"},{"key":"e_1_2_12_179_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.13282"},{"key":"e_1_2_12_180_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.3c09530"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.06\u20100140"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2010.05.002"},{"key":"e_1_2_12_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2018.03.008"},{"key":"e_1_2_12_184_1","doi-asserted-by":"publisher","DOI":"10.2174\/1872214809666150806105737"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543780903321490"},{"key":"e_1_2_12_186_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.02.057"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00031.2008"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13020\u2010021\u201000449\u20108"},{"key":"e_1_2_12_189_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.23.22.8137\u20108151.2003"},{"key":"e_1_2_12_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.155897"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010023\u201051083\u20103"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2017.4402"},{"key":"e_1_2_12_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2017.08.006"},{"key":"e_1_2_12_194_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.11850"},{"key":"e_1_2_12_195_1","doi-asserted-by":"publisher","DOI":"10.1039\/c8fo01699b"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c11188"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201900638"},{"key":"e_1_2_12_198_1","doi-asserted-by":"publisher","DOI":"10.1080\/10286020.2010.505188"},{"key":"e_1_2_12_199_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.4657"},{"key":"e_1_2_12_200_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27227868"},{"key":"e_1_2_12_201_1","doi-asserted-by":"publisher","DOI":"10.1002\/tox.23457"},{"key":"e_1_2_12_202_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241311004"},{"key":"e_1_2_12_203_1","doi-asserted-by":"publisher","DOI":"10.1039\/d0fo00172d"},{"key":"e_1_2_12_204_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.113887"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.70339","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ptr.70339","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.70339","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T18:17:30Z","timestamp":1783448250000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.70339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,21]]},"references-count":203,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/ptr.70339"],"URL":"https:\/\/doi.org\/10.1002\/ptr.70339","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,21]]},"assertion":[{"value":"2025-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}