{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:50:52Z","timestamp":1790686252924,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005972","name":"Deutsche Krebshilfe","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005972","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Respiratory viruses pose a significant threat to global health. They initially infect the naso\u2010 and oropharyngeal regions, where they amplify, cause symptoms, and may also be transmitted to new hosts. Preventing initial infection or reducing viral loads upon infection might soothe symptoms, prevent dissemination into the lower airways, or transmission to the next individual. Several natural products have well\u2010described direct antiviral activity or may ameliorate symptoms of respiratory infections. We thus analyzed the potential of plant\u2010derived products to inactivate respiratory viral pathogens and determined the antiviral activity of black chokeberry (\n                    <jats:italic>Aronia melanocarpae<\/jats:italic>\n                    [Michx.]\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/de.wikipedia.org\/wiki\/Stephen_Elliott_(Botaniker)\">Elliott<\/jats:ext-link>\n                    ), elderberry (\n                    <jats:italic>Sambucus nigra<\/jats:italic>\n                    L.), and pomegranate (\n                    <jats:italic>Punica granatum<\/jats:italic>\n                    L.) juice, as well as green tea (\n                    <jats:italic>Camellia sinensis<\/jats:italic>\n                    [L.] Kuntze) on the infectivity of the surrogate\u2010modified vaccinia virus Ankara, and the respiratory viruses severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102), influenza A virus (IAV), and adenovirus Type 5. Black chokeberry and pomegranate juice, and green tea reduced SARS\u2010CoV\u20102 and IAV titers by \u226580% or \u226599%. This suggests that oral rinsing with these products may reduce viral loads in the oral cavity which might prevent viral transmission.\n                  <\/jats:p>","DOI":"10.1002\/ptr.7431","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T05:12:08Z","timestamp":1646111528000},"page":"2109-2115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Antiviral activity of plant juices and green tea against\n                    <scp>SARS\u2010CoV<\/scp>\n                    \u20102 and influenza virus"],"prefix":"10.1002","volume":"36","author":[{"given":"Maren","family":"Eggers","sequence":"first","affiliation":[{"name":"Virologie Labor Prof. Dr. G. Enders MVZ GbR  Stuttgart Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peggy","family":"Jungke","sequence":"additional","affiliation":[{"name":"Technische Universit\u00e4t Dresden Medical Faculty Carl Gustav Carus  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Wolkinger","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Sciences University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0057-5547","authenticated-orcid":false,"given":"Rudolf","family":"Bauer","sequence":"additional","affiliation":[{"name":"Institute of Pharmaceutical Sciences University of Graz  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Kessler","sequence":"additional","affiliation":[{"name":"General management \/ R&amp;D CogniVerde GmbH  Im Oberen Rech 10 Gro\u00df\u2010Umstadt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Frank","sequence":"additional","affiliation":[{"name":"General management \/ R&amp;D CogniVerde GmbH  Im Oberen Rech 10 Gro\u00df\u2010Umstadt Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fdmed.2021.648547"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.57309"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/covid1010002"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2021.113438"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034520967933"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1437-1"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2021.26.3.2000708"},{"key":"e_1_2_8_9_1","unstructured":"European Chemicals Agency(2018). Guidance on the biocidal products regulation: Volume II efficacy \u2013 Assessment and evaluation (parts B + C) (Vol. V3 Issue April)."},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe2009758"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2009.06.002"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aimed.2020.08.001"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1177-4396"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.05.042"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-016-3083-0"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5630838"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01863914"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-016-2639-x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-021-00680-8"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa471"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2020.153286"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.JJID.2020.902"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/function\/zqaa002"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26123572"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2013.08.090"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06873-8"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-020-01563-9"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8295.1908.tb00176.x"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2010.06.014"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.638187"},{"issue":"9","key":"e_1_2_8_31_1","first-page":"1319","article-title":"Comparison of total phenolic contents (TPC) and antioxidant activities of fresh fruit juices, commercial 100% fruit juices and fruit drinks","volume":"45","author":"Wern K. H.","year":"2016","journal-title":"Sains Malaysiana"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22081337"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323000403200205"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1089\/acm.1995.1.361"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.7431","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ptr.7431","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.7431","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T23:08:04Z","timestamp":1692832084000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.7431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1002\/ptr.7431"],"URL":"https:\/\/doi.org\/10.1002\/ptr.7431","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.10.30.360545","asserted-by":"object"}]},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"2020-11-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}