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The analysis identified several herbs, including <jats:italic>Rosmarinus officinalis<\/jats:italic>, <jats:italic>Crocus sativus<\/jats:italic>, <jats:italic>Rosa damascena<\/jats:italic>, <jats:italic>Curcuma longa<\/jats:italic>, <jats:italic>Valeriana officinalis<\/jats:italic>, <jats:italic>Lactuca sativa<\/jats:italic>, <jats:italic>Portulaca oleracea<\/jats:italic>, <jats:italic>Citrus aurantium<\/jats:italic>, <jats:italic>Lippia citriodora<\/jats:italic>, and <jats:italic>Melissa officinalis<\/jats:italic>, which show promise in improving overall sleep time, reducing sleep latency, and enhancing sleep quality. These plants act on the central nervous system, particularly the serotonergic and gamma\u2010aminobutyric acid (GABA)ergic systems, promoting sedation and relaxation. However, further research is necessary to fully understand their mechanisms of action, optimal dosages, and treatment protocols. Combining herbal medicines with conventional treatments may offer an effective natural alternative for those seeking medication. Nevertheless, individuals should consult their healthcare provider before using herbal remedies for insomnia. While this review provides evidence supporting their use, additional high\u2010quality studies are needed to firmly establish their clinical efficacy.<\/jats:p>","DOI":"10.1002\/ptr.8201","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T07:19:24Z","timestamp":1712733564000},"page":"3037-3059","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Therapeutic potential of hypnotic herbal medicines: A comprehensive review"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5491-572X","authenticated-orcid":false,"given":"Mahboobeh","family":"Ghasemzadeh Rahbardar","sequence":"first","affiliation":[{"name":"Pharmaceutical Research Center Pharmaceutical Technology Institute, Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3483-851X","authenticated-orcid":false,"given":"Hossein","family":"Hosseinzadeh","sequence":"additional","affiliation":[{"name":"Pharmaceutical Research Center Pharmaceutical Technology Institute, Mashhad University of Medical Sciences  Mashhad Iran"},{"name":"Department of Pharmacodynamics and Toxicology School of Pharmacy, Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.26656\/fr.2017.4(6).363"},{"issue":"2","key":"e_1_2_12_3_1","first-page":"86","article-title":"The effect of Citrus aurantium aroma on the sleep quality in postmenopausal women: A randomized controlled trial","volume":"10","author":"Abbaspoor Z.","year":"2022","journal-title":"International Journal of Community\u2010Based Nursing and Midwifery"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2023.116602"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6894"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2013.11.016"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/jpnr.JPNR_16_17"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.5530\/pj.2023.15.52"},{"issue":"4","key":"e_1_2_12_9_1","first-page":"528","article-title":"The effect of ethanolic extract of Lippia citriodora on rats with chronic constriction injury of neuropathic pain","volume":"19","author":"Amin B.","year":"2018","journal-title":"Cell Journal"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5512"},{"issue":"3","key":"e_1_2_12_11_1","first-page":"297","article-title":"Effects of Valeriana officinalis (valerian) on tension\u2010type headache: A randomized, placebo\u2010controlled, double\u2010blind clinical trial","volume":"10","author":"Azizi H.","year":"2020","journal-title":"Avicenna Journal of Phytomedicine"},{"issue":"1","key":"e_1_2_12_12_1","first-page":"52","article-title":"The effect of damask rose extract on sleep quality in patients undergoing angiography admitted to cardiac care unit. 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