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Conventional therapies such as non\u2010steroidal anti\u2010inflammatory drugs (NSAIDs) such as allopurinol, corticosteroids and colchicine amongst others, have helped in its management and treatment to some extent. This study aimed to compile and analyze the different herbal remedies used in the management of hyperuricemia and gout. A literature search was conducted from key databases (PubMed, ScienceDirect, Cochrane Library, Google Scholar) using relevant keywords via the PRISMA model. <jats:italic>Smilax riparia<\/jats:italic> A.DC. from Traditional Chinese Medicine is used in many countries for its therapeutic effect on lowering serum urate levels. No single study was able to establish the efficacy of a specific traditionally used herb via in vitro, in vivo, and clinical studies. Patients were found to use a panoply of natural remedies, mainly plants to treat hyperuricemia and gout, which have been validated to some extent by in vitro, in vivo, and clinical studies. Nonetheless, further research is needed to better understand the ethnopharmacological relationship of such herbal remedies.<\/jats:p>","DOI":"10.1002\/ptr.8211","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T11:03:56Z","timestamp":1713956636000},"page":"3370-3400","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Herbal remedies in the management of hyperuricemia and gout: A review of in vitro, in vivo and clinical evidences"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3962-8666","authenticated-orcid":false,"given":"Mohamad Fawzi","family":"Mahomoodally","sequence":"first","affiliation":[{"name":"Institute of Research and Development Duy Tan University  Da Nang Vietnam"},{"name":"School of Engineering &amp; Technology Duy Tan University  Da Nang 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