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Peroxynitrite was scavenged by the presence of various flavonoids, whose structures seem to be closely related to the degree of scavenging. Of 31 compounds tested, the most active was quercetin, with an IC<jats:sub>50<\/jats:sub> value of 0.93\u2005\u03bc<jats:sc>M<\/jats:sc>. Others had IC<jats:sub>50<\/jats:sub> values ranging from 0.96 to more than 10\u2005\u03bc<jats:sc>M<\/jats:sc>. The scavenging activity was postulated to be governed by the position of the hydroxyl group. <jats:italic>Ortho<\/jats:italic>\u2010hydroxyl structures increased the scavenging activity on peroxynitrite. 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