{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:07:55Z","timestamp":1787166475677,"version":"build-2736575974"},"reference-count":159,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T00:00:00Z","timestamp":1722902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81874449"],"award-info":[{"award-number":["81874449"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82274481"],"award-info":[{"award-number":["82274481"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2022LZY004"],"award-info":[{"award-number":["ZR2022LZY004"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease. Abnormal formation of neutrophil extracellular traps (NETs) at the synovial membrane leads to the release of many inflammatory cytokines, including IL\u20101\u03b2, IL\u20106, and TNF\u2010\u03b1. Elastase, histone H3, and myeloperoxidase, which are carried by NETs, damage the soft tissues of the joints and aggravate the progression of RA. The balance of NET formation coordinates the pro\u2010inflammatory and anti\u2010inflammatory effects and plays a key role in the development of RA. Therefore, when NETs are used as effector targets, highly targeted drugs with fewer side effects can be developed to treat RA without damaging the host immune system. Currently, an increasing number of studies have shown that traditional Chinese medicines and natural products can regulate the formation of NETs through multiple pathways to counteract RA, which shows great potential for the treatment of RA and has a promising future for clinical application. In this article, we review the latest biological progress in understanding NET formation, the mechanism of NETs in RA, and the potential targets or pathways related to the modulation of NET formation by Chinese medicines and natural products. This review provides a relevant basis for the use of Chinese medicines and natural products as natural adjuvants in the treatment of RA.<\/jats:p>","DOI":"10.1002\/ptr.8311","type":"journal-article","created":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T07:01:55Z","timestamp":1722927715000},"page":"5067-5087","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Neutrophil extracellular traps: Potential targets for the treatment of rheumatoid arthritis with traditional Chinese medicine and natural products"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8961-4743","authenticated-orcid":false,"given":"Yuan","family":"Liu","sequence":"first","affiliation":[{"name":"The first Clinical Medical College Shandong University of Chinese Traditional Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Qu","sequence":"additional","affiliation":[{"name":"The first Clinical Medical College Shandong University of Chinese Traditional Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanguo","family":"Liu","sequence":"additional","affiliation":[{"name":"Experimental Center Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Zhang","sequence":"additional","affiliation":[{"name":"Rheumatology and Immunology Department The Affiliated Hospital of Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Xu","sequence":"additional","affiliation":[{"name":"Rheumatology and Immunology Department The Affiliated Hospital of Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yakun","family":"Wan","sequence":"additional","affiliation":[{"name":"School of Rehabilitation Medicine Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Jiang","sequence":"additional","affiliation":[{"name":"The first Clinical Medical College Shandong University of Chinese Traditional Medicine  Jinan China"},{"name":"Rheumatology and Immunology Department The Affiliated Hospital of Shandong University of Traditional Chinese Medicine  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208870"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-56153-6_2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-018-0039-z"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41062"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27217223"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.118286"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.112643"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24213961"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/cei\/uxac093"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2019.11.009"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.651049"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26010005"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-020-01294-x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.139388"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aag3358"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab845"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10071604"},{"key":"e_1_2_10_19_1","first-page":"2400","article-title":"Clinical observation on Wangbi tablet treating on early rheumatoid arthritis with syndrome of liver and kidney deficiency and syndrome of wind\u2010dampness blocking collaterals","volume":"36","author":"Chen L.","year":"2021","journal-title":"Journal of Chinese Traditional and Herbal Drugs"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21060710"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01452-1"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.108746"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2021.114178"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.47102\/annals-acadmedsg.2023112"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04126-3"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13040630"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0459-4"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-020-00715-5"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2018.08.014"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2020.102484"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24054896"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2021-004037"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.636954"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5631"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1414055112"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2021.0013"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13735"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.118.311150"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9040915"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.649693"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.69"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005743107"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02481"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-21-3522"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S266911"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom9080369"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2023.102787"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1875-5364(16)30079-6"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2015.10.005"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.686155"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2022.105346"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2016.01.015"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(93)90046-b"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201701148RR"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-30922-3"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2022.116119"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107879"},{"key":"e_1_2_10_58_1","first-page":"616","article-title":"Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential","volume":"12","author":"Jones J. E.","year":"2009","journal-title":"Current Opinion in Drug Discovery & Development"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009742.2019.1641216"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27196474"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13412"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.24437"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/710239"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00380"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.3844\/ajptsp.2014.200.202"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1080\/14728222.2017.1294160"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2018.12.033"},{"key":"e_1_2_10_68_1","first-page":"208","article-title":"Neutrophil extracellular traps: Formation and involvement in disease progression","volume":"17","author":"Kumar S.","year":"2018","journal-title":"Iranian Journal of Allergy, Asthma, and Immunology"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2020-0410OC"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab050"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1190607"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00307"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/7022337"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-022-00568-4"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20100239"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20205035"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.962968"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15313"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.2478\/rir-2022-0020"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4027"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8589121"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11684-018-0649-5"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1023\/a:1007029524141"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph14040309"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.2478\/aite-2024-0014"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1159\/000522331"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2023-003104"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1756-185X.2011.01656.x"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1080\/08830185.2021.1921174"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19412-6"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01849"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389201020666190102150216"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-1226"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxins15010044"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd2688"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.715997"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2022-223568"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11244070"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23881-8"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201646542"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1211601"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-213223"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1080\/08916934.2018.1519804"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-9424-3_31"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10112857"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom9080365"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.05.006"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00360"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.2c00387"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.109843"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2021.1899811"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1017\/S002966511000162X"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.22980"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2014.10.031"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.88912"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.0786"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-22-5720"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-22021-6"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-009-0193-1"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh202"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12841"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.3RU0620-375R"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S364759"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1177\/2058739218805667"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02036"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1909546117"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573397116666201221113100"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2022.121334"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.107602"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.23298"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202350823"},{"issue":"6","key":"e_1_2_10_132_1","first-page":"6917","article-title":"Ephedra\u2010almond herbal pair inhibits formation of NETs by inhibiting the HMGB1\/TLR4 signaling pathway","volume":"12","author":"Wang Q.","year":"2019","journal-title":"International Journal of Clinical and Experimental Medicine"},{"key":"e_1_2_10_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.09.027"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11655-018-2847-z"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2013.09.021"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2014.80"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21114015"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22020686"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.117063"},{"key":"e_1_2_10_140_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.961708"},{"key":"e_1_2_10_141_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-012-8329-8"},{"key":"e_1_2_10_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2019.105919"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2018.06.003"},{"key":"e_1_2_10_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113249"},{"key":"e_1_2_10_145_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0590-9"},{"key":"e_1_2_10_146_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-04-457671"},{"key":"e_1_2_10_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcms.2017.05.007"},{"key":"e_1_2_10_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2020.108454"},{"key":"e_1_2_10_149_1","doi-asserted-by":"crossref","unstructured":"Zeng K.\u2010W. Wang W. Zhang Z.\u2010Q. Zhang Y.\u2010C. Wu Y.\u2010Q. Yang Z. Zheng Y. Z. Lu J. H. & Tu P. (2023).Anti\u2010rheumatoid arthritis effects ofCayratia albifoliaC.L.Li via inhibition of macrophage activation and neutrophil extracellular traps (nets).https:\/\/doi.org\/10.2139\/ssrn.4486677","DOI":"10.2139\/ssrn.4486677"},{"key":"e_1_2_10_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2019.04.033"},{"key":"e_1_2_10_151_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12993"},{"key":"e_1_2_10_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnma.2017.02.007"},{"key":"e_1_2_10_153_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21762"},{"key":"e_1_2_10_154_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7896738"},{"key":"e_1_2_10_155_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2023.12146"},{"key":"e_1_2_10_156_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/1240967"},{"key":"e_1_2_10_157_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14112414"},{"key":"e_1_2_10_158_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1086078"},{"key":"e_1_2_10_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2019.05.010"},{"key":"e_1_2_10_160_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3990607"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.8311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T22:49:21Z","timestamp":1731538161000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.8311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,6]]},"references-count":159,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/ptr.8311"],"URL":"https:\/\/doi.org\/10.1002\/ptr.8311","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,6]]},"assertion":[{"value":"2024-02-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}