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Environmental factors such as stress, infections, and injuries all play an important role in the disease's development. Although there is no cure for this disease, topical, oral, and systemic whole\u2010body treatments are available to relieve symptoms. Several plants and phytochemicals which have been found effective in the management of the psoriasis experimentally (preclinical and clinical). These plants\/phytochemicals have applications in topical, oral, and systemic treatments. Traditionally, some of the plants have been utilized as the primary treatment, including their extracts and\/or phytochemicals, for individuals with moderate to severe psoriasis (due to fewer side effects), while phototherapy is generally reserved for more advanced cases. This report describes various plants and phytochemicals that have been found to be effective against psoriasis in in\u00a0vitro, preclinical, and clinical studies. This review summarizes the key findings from experimental studies on various pathological aspects of psoriasis and may be useful, effective, and informative for future research.<\/jats:p>","DOI":"10.1002\/ptr.8405","type":"journal-article","created":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T07:09:31Z","timestamp":1735974571000},"page":"1139-1173","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Outline of Therapeutic Potential of Different Plants Reported Against Psoriasis via In\u00a0Vitro, Pre\u2010Clinical or Clinical Studies"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7201-1356","authenticated-orcid":false,"given":"Pawan","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Chemistry Shri Vile Parle Kelavani Mandal's Institute of Pharmacy  Dhule India"},{"name":"Research and Development Cell Lovely Professional University  Phagwara India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhakar","family":"Kalvatala","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences Lovely Professional University  Phagwara India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhinav","family":"Joseph","sequence":"additional","affiliation":[{"name":"Research and Development Cell Lovely Professional University  Phagwara India"},{"name":"School of Chemical Engineering and Physical Sciences Lovely Professional University  Phagwara India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3925-7631","authenticated-orcid":false,"given":"Anil","family":"Panghal","sequence":"additional","affiliation":[{"name":"Department of Processing and Food Engineering Chaudhary Charan Singh Haryana Agricultural University  Hisar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4304-4030","authenticated-orcid":false,"given":"Soumava","family":"Santra","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering and Physical Sciences Lovely Professional University  Phagwara India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,4]]},"reference":[{"key":"e_1_2_13_2_1","first-page":"1","article-title":"Medicinal Plants to Calm and Treat Psoriasis Disease","volume":"2016","author":"Aghmiuni A. 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