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In particular, by using physical chemistry methods, we are able to examine the chemical components of plants and the effects of these substances on the human body. Muscle atrophy (MA) is characterized by decreased muscle mass and function, is caused by multiple factors and severely affects the quality of life of patients. The multifactorial and complex pathogenesis of MA hinders drug research and disease treatment. However, phytotherapy has achieved significant results in the treatment of MA. We searched PubMed and the Web of Science for articles related to plant\u2010derived substances and muscle atrophy. After applying exclusion and inclusion criteria, 166 and 79 articles met the inclusion criteria, respectively. A total of 173 articles were included in the study after excluding duplicates. The important role of phytoactives such as curcumin, resveratrol, and ginsenosides in the treatment of MA (e.g., maintaining a positive nitrogen balance in muscles and exerting anti\u2010inflammatory and antioxidant effects) has been extensively studied. Unfortunately, MA dose not have to a single cause, and each cause has its own unique mechanism of injury. This review focuses on the therapeutic mechanisms of active plant components in MA and provides insights into the personalized treatment of MA.<\/jats:p>","DOI":"10.1002\/ptr.8420","type":"journal-article","created":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T03:10:47Z","timestamp":1735787447000},"page":"1107-1138","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Plant\u2010Derived Treatments for Different Types of Muscle Atrophy"],"prefix":"10.1002","volume":"39","author":[{"given":"Xingpeng","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Spine Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofu","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery Shandong Provincial Hospital Affiliated to Shandong First Medical University  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