{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:03:37Z","timestamp":1772118217836,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2002,5,15]],"date-time":"2002-05-15T00:00:00Z","timestamp":1021420800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phytotherapy Research"],"published-print":{"date-parts":[[2002,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Goodyerin is a flavonol glycoside isolated from the whole plants of <jats:italic>Goodyera schlechtendaliana<\/jats:italic> which has been used as a substitute for the crude drug, <jats:italic>Anoectochilus formosanus<\/jats:italic>. The pharmacological properties of goodyerin were assayed for effects on spontaneous locomotor activity, on pentobarbital\u2010induced hypnosis, and on anticonvulsant activity against picrotoxin\u2010induced seizures in rodents. Goodyerin exhibited a significant and dose\u2010dependent sedative and anticonvulsant effect. Copyright \u00a9 2002 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/ptr.862","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T23:48:25Z","timestamp":1030319305000},"page":"261-263","source":"Crossref","is-referenced-by-count":28,"title":["Sedative and anticonvulsant activities of goodyerin, a flavonol glycoside from<i> Goodyera schlechtendaliana<\/i>"],"prefix":"10.1002","volume":"16","author":[{"given":"Xiao\u2010Ming","family":"Du","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning\u2010Yi","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanako","family":"Takizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong\u2010Tian","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Shoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,5,15]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"353","article-title":"Studies on Acorus culmus: pharmacological actions of essential oil","volume":"125","author":"Dandiya PC","year":"1959","journal-title":"J Pharmac Exp Ther"},{"key":"e_1_2_1_3_1","first-page":"3","article-title":"New wave of research in the epilepsies","volume":"4","author":"Delgado\u2010Escueta AV","year":"1986","journal-title":"Adv Neurol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(00)00027-3"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-2911-2"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(99)00011-8"},{"key":"e_1_2_1_7_1","first-page":"2282","volume-title":"Dictionary of the Traditional Chinese Medicines","year":"1986"},{"key":"e_1_2_1_8_1","first-page":"647","volume-title":"Pharmaceutical Botany","author":"Kan WS","year":"1986"},{"key":"e_1_2_1_9_1","first-page":"262","article-title":"Pharmacognostical studies on the crude drugs of Orchidaceae from Taiwan (VI) on Kim\u2010soan\u2010lian (1)","volume":"35","author":"Lin C\u2010C","year":"1981","journal-title":"Shoyakugaku Zasshi"},{"key":"e_1_2_1_10_1","first-page":"272","article-title":"Pharmacognostical studies on the crude drugs of Orchidaceae from Taiwan (VII) on Kim\u2010soan\u2010lian (2)","volume":"35","author":"Lin C\u2010C","year":"1981","journal-title":"Shoyakugaku Zasshi"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01243417"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(90)90716-X"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1986.tb05731.x"},{"key":"e_1_2_1_14_1","first-page":"619","volume-title":"The Flavonoids, Advances in Research Since 1986","author":"Middleton E","year":"1994"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1211\/0022357991772790"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(84)90282-6"},{"key":"e_1_2_1_17_1","first-page":"287","article-title":"The application of the measuring apparatus of locomotor activity by infrared sensor system using multi\u2010Fresnal lenses to forced swimming test","volume":"19","author":"Sugiura M","year":"1997","journal-title":"Jpn J Neuropsychopharmacol"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-958058"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-3057(94)90103-1"}],"container-title":["Phytotherapy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fptr.862","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ptr.862","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T08:14:01Z","timestamp":1700295241000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ptr.862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["10.1002\/ptr.862"],"URL":"https:\/\/doi.org\/10.1002\/ptr.862","archive":["Portico"],"relation":{},"ISSN":["0951-418X","1099-1573"],"issn-type":[{"value":"0951-418X","type":"print"},{"value":"1099-1573","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,5]]}}}