{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:40:34Z","timestamp":1792453234328,"version":"4.5.0"},"reference-count":52,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"vor","delay-in-days":52,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Chronic thromboembolic pulmonary hypertension may be cured by pulmonary endarterectomy\u00a0(PEA). Thromboembolic disease distribution\/PEA success primarily determines prognosis but risk scoring criteria may be adjunctive. Right ventriculoarterial (RV\u2010PA) and ventriculoatrial (RV\u2010right atrium [RA]) coupling may be evaluated by cardiac MRI (CMR) feature tracking deformation\/strain assessment. We characterized biatrial and biventricular CMR feature tracking\u00a0(FT) strain parameters following PEA\u00a0and tested the ability of CMR FT to identify REVEAL 2.0 high\u2010risk status. We undertook a retrospective single\u2010center cross\u2010sectional study of patients (<jats:italic>n<\/jats:italic>\u2009=\u200957) who underwent PEA (2015\u20132020). All underwent pre and postoperative catheterization and CMR. Pulmonary arterial hypertension validated risk scores were calculated. Significant postoperative improvements were observed in mean pulmonary artery pressure\u00a0(mPAP) (pre\u2010op 45\u2009\u00b1\u200911\u2009mmHg vs. post\u2010op 26\u2009\u00b1\u200911\u2009mmHg; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and PVR however a large proportion had residual pulmonary hypertension (45%; mPAP \u226525\u2009mmHg). PEA augmented left heart filling with left ventricular end diastolic volume index and left atrial volume index increment. Left ventricular ejection fraction was unchanged postoperatively but LV global longitudinal strain improved (pre\u2010op median \u221214.2% vs. post\u2010op \u221216.0%; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Right ventricular (RV) geometry and function also improved with reduction in RV mass. Most had uncoupled RV\u2010PA relationships which recovered (pre\u2010op right ventricular free wall longitudinal strain \u221213.2\u2009\u00b1\u20094.8%, RV stroke volume\/right ventricular end systolic volume ratio 0.78\u2009\u00b1\u20090.53 vs. post\u2010op \u221216.8\u2009\u00b1\u20094.2%, 1.32\u2009\u00b1\u20090.55; both <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Postoperatively, there were six\u00a0REVEAL 2.0 high\u2010risk patients, best predicted by impaired RA strain which was superior to traditional volumetric parameters (area under the curve [AUC] 0.99 vs.\u00a0RVEF AUC 0.88). CMR deformation\/strain evaluation can offer insights into coupling recovery; RA strain may be an expeditious surrogate for the more laborious REVEAL 2.0 score.<\/jats:p>","DOI":"10.1002\/pul2.12116","type":"journal-article","created":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T12:53:34Z","timestamp":1657889614000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Utility of cardiac magnetic resonance feature tracking strain assessment in chronic thromboembolic pulmonary hypertension for prediction of REVEAL 2.0 high risk status"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5556-9825","authenticated-orcid":false,"given":"Kai'En","family":"Leong","sequence":"first","affiliation":[{"name":"Department of Radiology Imperial College Healthcare NHS Trust\/Hammersmith Hospital London UK"},{"name":"Department of Cardiology The Royal Melbourne Hospital Victoria 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