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Data from the referral center electronic medical record database were linked to the National Health Service Hospital Episode Statistics database to collect and analyze patient demographics, clinical characteristics, comorbidities, treatment patterns, health\u2010related quality of life (HRQoL; assessed using the EmPHasis\u201010 questionnaire), healthcare resource utilization (HCRU), costs, and survival. Sixty\u2010two patients with SAPH were identified. At diagnosis, 84% were in WHO functional class III and presented with significant pulmonary hemodynamic impairment. Cardiovascular and respiratory comorbidities were commonly reported prediagnosis. Median EmPHasis\u201010 score at diagnosis was 34, indicative of poor HRQoL. In the 1st year after diagnosis, median (Q1, Q3) per\u2010patient HCRU was 1 (0, 2) all\u2010cause inpatient hospitalizations; 3 (2, 4) same\u2010day hospitalizations; and 9 (6, 11) outpatient consultations. In 24 patients who were hospitalized longer than 1 day in the 1st year after diagnosis, the median duration of hospitalization was 4 days. With a median follow\u2010up of 1.8 years, the median overall survival was 2.9 years. In this cohort of patients with SAPH, poor HRQoL and high HCRU were observed following diagnosis. To our knowledge, this is the first study to report on HRQoL and HCRU in patients with SAPH. More research is needed on treatment options for this population with high unmet needs.<\/jats:p>","DOI":"10.1002\/pul2.12136","type":"journal-article","created":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T14:54:58Z","timestamp":1662994498000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Healthcare resource utilization and quality of life in patients with sarcoidosis\u2010associated pulmonary hypertension"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4192-9505","authenticated-orcid":false,"given":"Allan","family":"Lawrie","sequence":"first","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London London UK"},{"name":"Insigneo Institute for In\u2010Silico Medicine University of Sheffield Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Sheffield Pulmonary Vascular Disease Unit Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Wood","sequence":"additional","affiliation":[{"name":"Insigneo Institute for In\u2010Silico Medicine University of Sheffield Sheffield UK"},{"name":"Scientific Computing, Sheffield Teaching Hospitals NHS Foundation Trust Royal Hallamshire Hospital Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Exposto","sequence":"additional","affiliation":[{"name":"IQVIA London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruvimbo","family":"Muzwidzwa","sequence":"additional","affiliation":[{"name":"IQVIA London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Raiteri","sequence":"additional","affiliation":[{"name":"IQVIA London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Am\u00e9lie","family":"Beaudet","sequence":"additional","affiliation":[{"name":"Actelion Pharmaceuticals Ltd. 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