{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T14:46:25Z","timestamp":1769265985040,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T00:00:00Z","timestamp":1669161600000},"content-version":"vor","delay-in-days":53,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Klippel\u2013Trenaunay\u2013Weber syndrome (KTWS) is a rare congenital disorder characterized by cutaneous capillary malformations, bone hypertrophy, and multiple venous or lymphatic malformations. KTWS is associated with chronic thromboembolic pulmonary hypertension (CTEPH), presumably due to thromboembolism from multiple vascular malformations. Here, we report the first case series of patients with KTWS\u2010CTEPH who underwent balloon pulmonary angioplasty (BPA). Both patients are alive 20 years and 1 year after the initial diagnosis of CTEPH, respectively, and are stable with improved hemodynamics. BPA may be an effective treatment option for patients with KTWS\u2010CTEPH.<\/jats:p>","DOI":"10.1002\/pul2.12155","type":"journal-article","created":{"date-parts":[[2022,11,8]],"date-time":"2022-11-08T13:46:52Z","timestamp":1667915212000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension concomitant with Klippel\u2013Trenaunay\u2013Weber syndrome"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5257-9865","authenticated-orcid":false,"given":"Takeshi","family":"Suetomi","sequence":"first","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Okayama Medical Center Okayama Japan"},{"name":"Department of Medicine and Clinical Science,\u00a0Division of Cardiology Yamaguchi University Ube Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroto","family":"Shimokawahara","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Okayama Medical Center Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichi","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Okayama Medical Center Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayane","family":"Miyagi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Okayama Medical Center Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aiko","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Okayama Medical Center Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari","family":"Nishizaki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Okayama Medical Center Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Matsubara","sequence":"additional","affiliation":[{"name":"Department of Cardiology, National Hospital Organization Okayama Medical Center Okayama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1258\/026835507782655209"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.115.4.1199"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(95)70199-0"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800720331"},{"issue":"5","key":"e_1_2_8_6_1","first-page":"246","article-title":"Venous thromboembolism and prothrombotic parameters in Klippel\u2010Trenaunay syndrome","volume":"71","author":"Oduber CE","year":"2013","journal-title":"Neth J Med"},{"issue":"4","key":"e_1_2_8_7_1","first-page":"e7576","article-title":"Recurrent venous thromboembolism in a patient with Klippel\u2010Trenaunay syndrome despite adequate anticoagulation with warfarin","volume":"12","author":"Asnake ZT","year":"2020","journal-title":"Cureus"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.117.5.1520"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmer.2019.06.002"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(16)30022-4"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.117.004029"}],"container-title":["Pulmonary Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pul2.12155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pul2.12155","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pul2.12155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T23:08:57Z","timestamp":1692313737000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pul2.12155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/pul2.12155"],"URL":"https:\/\/doi.org\/10.1002\/pul2.12155","archive":["Portico"],"relation":{},"ISSN":["2045-8940","2045-8940"],"issn-type":[{"value":"2045-8940","type":"print"},{"value":"2045-8940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"2022-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12155"}}