{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T22:09:31Z","timestamp":1758406171190,"version":"3.41.2"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":60,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) patients have a more severe COVID\u201019 course than the general population. Many patients report different persistent symptoms after SARS\u2010CoV\u20102 infection. The aim of our study is to analyze the prevalence of long COVID\u201019 symptoms and assess if COVID\u201019 affects pulmonary hypertension (PH) prognosis. PAH\/CTEPH patients who survived COVID\u201019 for at least 3 months before visiting the PH centers were included in the study. The patients were assessed for symptoms in acute phase of SARS\u2010CoV\u20102 infection and persisting in follow\u2010up visit, WHO functional class, 6\u2010min walk distance, NT\u2010proBNP concentration. The COMPERA 2.0 model was used to calculate 1\u2010year risk of death due to PH at baseline and at follow\u2010up. Sixty\u2010nine patients\u201454 (77.3%) with PAH and 15 (21.7%) with CTEPH, 68% women, with a median age of 47.5 years (IQR 37\u201368)\u2014were enrolled in the study. About 17.1% of patients were hospitalized due to COVID\u201019 but none in an ICU. At follow\u2010up (median: 155 days after onset of SARS\u2010CoV\u20102 symptoms), 62% of patients reported at least 1 COVID\u201019\u2010related symptom and 20% at least 5 symptoms. The most frequently reported symptoms were: fatigue (30%), joint pain (23%), muscle pain (17%), nasal congestion (17%), anosmia (13%), insomnia (13%), and dyspnea (12%). Seventy\u2010two percent of PH patients had a low or intermediate\u2010low risk of 1\u2010year death due to PH at baseline, and 68% after COVID\u201019 at follow\u2010up. Over 60% of PAH\/CTEPH patients who survived COVID\u201019 suffered from long COVID\u201019 syndrome, but the calculated 1\u2010year risk of death due to PH did not change significantly after surviving mild or moderate COVID\u201019.<\/jats:p>","DOI":"10.1002\/pul2.12244","type":"journal-article","created":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:47:35Z","timestamp":1685580455000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Long COVID syndrome after SARS\u2010CoV\u20102 survival in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6848-5698","authenticated-orcid":false,"given":"Maria","family":"Wieteska\u2010Mi\u0142ek","sequence":"first","affiliation":[{"name":"Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock Centre of Postgraduate Medical Education, Member of ERN Lung Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beata","family":"Ku\u015bmierczyk\u2010Droszcz","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease National Institute of Cardiology Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Betkier\u2010Lipi\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Internal Diseases Military Institute of Medicine\u2010National Research Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3075-1943","authenticated-orcid":false,"given":"Sebastian","family":"Szmit","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock Centre of Postgraduate Medical Education, Member of ERN Lung Warsaw Poland"},{"name":"Cardio\u2010Oncology Department, Centre of Postgraduate Education Institute of Hematology Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4995-9645","authenticated-orcid":false,"given":"Micha\u0142","family":"Florczyk","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock Centre of Postgraduate Medical Education, Member of ERN Lung Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5662-8866","authenticated-orcid":false,"given":"Piotr","family":"Zieli\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Military Institute of Medicine\u2010National Research Institute Legionowo Hospital Legionowo Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Department of Congenital Heart Disease National Institute of Cardiology Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1909-0993","authenticated-orcid":false,"given":"Pawe\u0142","family":"Krzesi\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Internal Diseases Military Institute of Medicine\u2010National Research Institute Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6746-469X","authenticated-orcid":false,"given":"Marcin","family":"Kurzyna","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, European Health Centre Otwock Centre of Postgraduate Medical Education, Member of ERN Lung Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac237"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01913-2018"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9010173"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02828-2020"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/20406223211002961"},{"key":"e_1_2_9_7_1","unstructured":"World Health Organiozation General Director\u2010Speaches. General's opening remarks at the media briefing on COVID\u201019\u201011 March 2020. [cited 2023 Feb 2]. 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