{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T20:46:01Z","timestamp":1793652361118,"version":"4.5.1"},"reference-count":56,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":38,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Pulmonary hypertension (PH) results in increased morbidity and mortality in patients with interstitial lung disease (ILD). Early recognition of PH in this population is essential for planning diagnostic testing, initiating therapy, and evaluating for lung transplantation. The previously developed PH\u2010ILD Detection tool has significant potential in the evaluation and treatment of ILD patients; the aim of this study was to validate the tool in an independent, multicenter cohort of patients. We conducted a retrospective review of prospectively collected data from 161 ILD patients. Patients were stratified into low\u2010 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200978, 48.4%), intermediate\u2010 (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200954, 33.5%), and high\u2010risk (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200929, 18.0%) groups based on the score obtained with the tool. Intermediate\u2010 and high\u2010risk patients underwent follow\u2010up echocardiogram (TTE); 49.4% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200941) had an abnormal TTE suggestive of underlying PH. These patients underwent right heart catheterization; PH\u2010ILD was diagnosed in 73.2% (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200930) of these cases. The PH\u2010ILD Detection tool has a sensitivity of 93.3%, specificity of 90.9%, and area\u2010under\u2010the\u2010curve of 0.921 for diagnosing PH in ILD patients, validating the findings from the original study and establishing the tool as a fundamental resource for early recognition of PH in ILD patients.\n                  <\/jats:p>","DOI":"10.1002\/pul2.12273","type":"journal-article","created":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T02:44:12Z","timestamp":1691549052000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["The PH\u2010ILD Detection tool: External validation and use in patients with ILD"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3063-6002","authenticated-orcid":false,"given":"Raj","family":"Parikh","sequence":"first","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep, Hartford Hospital Hartford Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"Department of Research Administration Hartford HealthCare Hartford Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0297-7902","authenticated-orcid":false,"given":"Harrison W.","family":"Farber","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Sleep and Critical Care Medicine, Tufts Medical Center Boston Massachusetts 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