{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T09:08:57Z","timestamp":1784624937311,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T00:00:00Z","timestamp":1713657600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Echocardiography is a widely used modality for the assessment of right ventricular (RV) function; however, few studies have comprehensively compared the accuracy of echocardiographic parameters using invasively obtained reference values. Therefore, this exploratory study aimed to compare the accuracy of echocardiographic parameters of RV function and RV\u2013pulmonary artery (PA) coupling. We calculated four indices of RV function (end\u2010systolic elastance [Ees] for systolic function [contractility], <jats:italic>\u03c4<\/jats:italic> for relaxation, and <jats:italic>\u03b2<\/jats:italic> and end\u2010diastolic elastance [Eed] for stiffness), and an index of RV\u2013PA coupling (Ees\/arterial elastance [Ea]), using pressure catheterization, cardiac magnetic resonance imaging, and a single\u2010beat method. We then compared the correlations of RV indices with echocardiographic parameters. In 63 participants (54 with pulmonary hypertension (PH) and nine without PH), Ees and <jats:italic>\u03c4<\/jats:italic> correlated with several echocardiographic parameters, such as RV diameter and area, but the correlations were moderate (|correlation coefficients (<jats:italic>\u03c1<\/jats:italic>)|\u2009&lt;\u20090.5 for all parameters). The correlations of <jats:italic>\u03b2<\/jats:italic> and Eed with echocardiographic parameters were weak, with |<jats:italic>\u03c1<\/jats:italic>|\u2009&lt;\u20090.4. In contrast, Ees\/Ea closely correlated with RV free wall longitudinal strain (RVFW\u2010LS)\/estimated systolic PA pressure (eSPAP) (<jats:italic>\u03c1<\/jats:italic>\u2009=\u2009\u22120.72). Ees\/Ea also correlated with tricuspid annular plane systolic excursion\/eSPAP, RV diameter, and RV end\u2010systolic area, with |<jats:italic>\u03c1<\/jats:italic>\u2009|\u2009&gt;0.65. In addition, RVFW\u2010LS\/eSPAP yielded high sensitivity (0.84) and specificity (0.75) for detecting reduced Ees\/Ea. The present study indicated a limited accuracy of echocardiographic parameters in assessing RV systolic and diastolic function. In contrast to RV function, they showed high accuracy for assessing RV\u2013PA coupling, with RVFW\u2010LS\/eSPAP exhibiting the highest accuracy.<\/jats:p>","DOI":"10.1002\/pul2.12368","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T06:39:26Z","timestamp":1713767966000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Exploratory analysis of the accuracy of echocardiographic parameters for the assessment of right ventricular function and right ventricular\u2013pulmonary artery coupling"],"prefix":"10.1002","volume":"14","author":[{"given":"Hideki","family":"Shima","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Faculty of Medicine Hokkaido University Sapporo 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