{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T14:38:42Z","timestamp":1772548722304,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T00:00:00Z","timestamp":1734652800000},"content-version":"vor","delay-in-days":80,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Pulmonary arterial hypertension (PAH) is a chronic progressive exacerbation of cardiopulmonary vascular disease. The patients' exercise endurance decreased progressively and the survival rate was low. Current basic therapy and targeted drug therapy can improve the quality of life (QoL) of PAH patients, but the long\u2010term efficacy and prognosis are not good. In this study, the female sexual function index (FSFI) scale, Health Promoting Life Style Profile (HPLPII), and emPHasis\u201010 were used to evaluate PAH patients' sexual function, health\u2010promoting behaviors and QoL. Their correlation and the moderating effect of health promoting behavior were conducted. In total, 306 female patients responded. Age ranged from 18 to 69 years old and the mean age was (38.049\u2009\u00b1\u200910.686). The average score of sexual function in female PAH patients was (21.703\u2009\u00b1\u20098.947) points, and the detection rate of sexual dysfunction was 51.307%. The average score of health\u2010promoting behaviors and QoL was (121.915\u2009\u00b1\u200913.507) points and (17.992\u2009\u00b1\u200910.245) points respectively. QoL was significantly negatively correlated with sexual function and health\u2010promoting behaviors, while sexual function was significantly positively correlated with health\u2010promoting behaviors. The health\u2010promoting behaviors of female patients with PAH has a moderating effect between sexual function and QoL. The sexual function, health\u2010promoting behaviors and QoL of female PAH patients were all at an general level. Improving the level of health\u2010promoting behaviors could reduce the negative predictive effect of sexual function on QoL.<\/jats:p>","DOI":"10.1002\/pul2.70031","type":"journal-article","created":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T09:29:33Z","timestamp":1734686973000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Relationship Between Sexual Function, Health\u2010Promoting Behaviors, and Quality of Life in Female Patients With Pulmonary Arterial Hypertension"],"prefix":"10.1002","volume":"14","author":[{"given":"Ting","family":"Luo","sequence":"first","affiliation":[{"name":"Clinical Nursing Teaching and Research Section, The Second Xiangya Hospital of Central South University Changsha Hunan China"},{"name":"Department of Cardiovascular Medicine The Second Xiangya Hospital of Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liu","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Pathology and Research, Office of the School of Basic Medicine Hunan University of Medicine Huaihua Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9975-7577","authenticated-orcid":false,"given":"Sisi","family":"Chen","sequence":"additional","affiliation":[{"name":"Clinical Nursing Teaching and Research Section, The Second Xiangya Hospital of Central South University Changsha Hunan China"},{"name":"Department of Cardiovascular Medicine The Second Xiangya Hospital of Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingzhi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine The Second Xiangya Hospital of Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,12,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcli.2022.01.003"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.10.043"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00879-2022"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2000348"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.16277"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.14797\/mdcvj.1308"},{"issue":"05","key":"e_1_2_12_8_1","first-page":"481","article-title":"Study on Health\u2010Related Quality of Life in Patients With Pulmonary Hypertension","volume":"36","author":"Yan W.","year":"2019","journal-title":"Chinese Journal of Circulation"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24065850"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2021.1927243"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15061579"},{"issue":"24","key":"e_1_2_12_12_1","first-page":"00155","article-title":"Health\u2010Related Quality of Life Across the Spectrum of Pulmonary Hypertension","volume":"0012","author":"Balasubramanian A.","year":"2024","journal-title":"Chest"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.705666"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-022-02056-1"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10508-022-02284-w"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/2045894018788277"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-023-02214-3"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pul2.12164"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy340"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjae.2022.09.002"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2023.2210838"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2020.103638"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-022-01652-x"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare9010060"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1159\/000525495"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa696"},{"issue":"2","key":"e_1_2_12_27_1","first-page":"48","article-title":"Development of a Modified Yoga Program for Pulmonary Hypertension: A Case Series","volume":"21","author":"Awdish R.","year":"2015","journal-title":"Alternative Therapies in Health and Medicine"},{"issue":"3","key":"e_1_2_12_28_1","article-title":"Exercise\u2010Based Rehabilitation Programmes for Pulmonary Hypertension","volume":"3","author":"Morris N. 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