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A review of records at Hokkaido University Hospital (2014\u20132024) identified four cases of PH, each with different etiologies, including pulmonary arterial hypertension, pulmonary veno\u2010occlusive disease, and microthromboembolism. Contributing factors included splenic atrophy, corticosteroid\u2010responsive inflammation, and potential drug\u2010induced vascular remodeling. Although transient PH usually resolves, late\u2010onset PH emphasizes the need for long\u2010term echocardiographic monitoring. These findings underscore the importance of individualized management, avoiding pulmonary vasodilators without proper evaluation, and addressing underlying conditions such as thrombotic microangiopathy or interstitial lung disease.<\/jats:p>","DOI":"10.1002\/pul2.70165","type":"journal-article","created":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T14:25:21Z","timestamp":1758464721000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pediatric Pulmonary Hypertension Associated With Treatment of Myeloproliferative Disorders and Malignant Tumors"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1277-6119","authenticated-orcid":false,"given":"Ayako","family":"Chida\u2010Nagai","sequence":"first","affiliation":[{"name":"Department of Pediatrics Hokkaido University Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukayo","family":"Terashita","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hokkaido University Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinsuke","family":"Hirabayashi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hokkaido University Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9257-5623","authenticated-orcid":false,"given":"Hirokuni","family":"Yamazawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hokkaido University Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hokkaido University Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Manabe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Hokkaido University Sapporo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01913-2018"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-012-1246-z"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2014.10.021"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.09.022"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00464-2016"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0156-2023"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtct.2021.05.017"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-130-6-199903160-00014"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.03.044"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030897"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2012.08.022"}],"container-title":["Pulmonary Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pul2.70165","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T05:49:24Z","timestamp":1758865764000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pul2.70165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/pul2.70165"],"URL":"https:\/\/doi.org\/10.1002\/pul2.70165","archive":["Portico"],"relation":{},"ISSN":["2045-8940","2045-8940"],"issn-type":[{"type":"print","value":"2045-8940"},{"type":"electronic","value":"2045-8940"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70165"}}