{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T18:23:23Z","timestamp":1767032603739,"version":"3.48.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":86,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This study evaluates the utility of CT\u2010derived PA\/A and RV\/LV ratios in distinguishing surgically accessible CTEPH from acute PE and negative controls.\u202fUnlike the RV\/LV ratio, PA\/A ratio was significantly higher in CTEPH patients compared to low and intermediate\/high\u2010risk acute PE cohorts, indicating its utility as a marker of clot chronicity.<\/jats:p>","DOI":"10.1002\/pul2.70223","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T16:57:40Z","timestamp":1766768260000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Leveraging Vascular Over Ventricular Ratios in Observational Chronic Thromboembolic Pulmonary Hypertension and Acute Pulmonary Embolism Cohorts to Decode Clot Chronicity on Computed Tomography Angiography"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2389-5704","authenticated-orcid":false,"given":"Jared","family":"Larson","sequence":"first","affiliation":[{"name":"Department of Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Khorasani","sequence":"additional","affiliation":[{"name":"Department of Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Laurenzo","sequence":"additional","affiliation":[{"name":"Department of Medicine Northwestern University Feinberg School of Medicine, Division of Pulmonary and Critical Care Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2759-9394","authenticated-orcid":false,"given":"Stephen","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Surgery Northwestern University Feinberg School of Medicine, Division of Cardiac Surgery Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Christopher","family":"Malaisrie","sequence":"additional","affiliation":[{"name":"Department of Surgery Northwestern University Feinberg School of Medicine, Division of Cardiac Surgery Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Schimmel","sequence":"additional","affiliation":[{"name":"Department of Medicine Northwestern University Feinberg School of Medicine, Division of Cardiology Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farbod","family":"Rahaghi","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Pulmonary and Critical Care, Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Cuttica","sequence":"additional","affiliation":[{"name":"Department of Medicine Northwestern University Feinberg School of Medicine, Division of Pulmonary and Critical Care Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"Mylvaganam","sequence":"additional","affiliation":[{"name":"Department of Medicine Northwestern University Feinberg School of Medicine, Division of Pulmonary and Critical Care Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.12.022"},{"issue":"66","key":"e_1_2_11_3_1","first-page":"2582","article-title":"Catheter\u2010Directed Therapies in Chronic Thromboembolic Pulmonary Hypertension","volume":"60","author":"Yang J.","year":"2022","journal-title":"European Respiratory Journal"},{"key":"e_1_2_11_4_1","unstructured":"J.LiandS.Sabri Aventus Thrombectomy System Pulmonary Embolism Clinical Study(ClincalTrials.gov 2024) https:\/\/clinicaltrials.gov\/study\/NCT05907564#collaborators-and-investigators."},{"key":"e_1_2_11_5_1","unstructured":"RAPIDAI Rapid PE rapidai.com(RAPIDAI 2024) https:\/\/www.rapidai.com\/rapid-pe."},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-22-00732"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2023.03.001"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/RTI.0b013e318271c2eb"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejro.2021.100384"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00059-024-05251-4"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-0363"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.5.1606"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-023-02781-2"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2020.07.008"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr108"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-1422"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xjon.2022.04.016"},{"issue":"61","key":"e_1_2_11_18_1","article-title":"Reproducibility of the Main Pulmonary Artery to Ascending Aorta Ratio (PA:A) in Real\u2010World, Non\u2010Research Chest CT Scans","volume":"50","author":"Biem H. J.","year":"2017","journal-title":"European Respiratory Journal"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00232-2019"}],"container-title":["Pulmonary Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pul2.70223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T18:18:14Z","timestamp":1767032294000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pul2.70223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/pul2.70223"],"URL":"https:\/\/doi.org\/10.1002\/pul2.70223","archive":["Portico"],"relation":{},"ISSN":["2045-8940","2045-8940"],"issn-type":[{"type":"print","value":"2045-8940"},{"type":"electronic","value":"2045-8940"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-03-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70223"}}