{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T18:10:04Z","timestamp":1784916604186,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"vor","delay-in-days":42,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    In patients with mitral regurgitation (MR), the role of invasive hemodynamics is not well defined. We evaluated the value of right heart catheterization (RHC) and the 2022 ESC\/ERS pulmonary hypertension (PH) definition prior to a mitral valve procedure for the prediction of PH several months thereafter. We studied 274 patients (mean age 68\u2009\u00b1\u200911 years) with at least moderate MR (84% degenerative, 11% functional, 5% combined) undergoing RHC (baseline) followed by surgical (70%) or transcatheter (30%) valve repair\/replacement who had an echocardiogram after a median follow\u2010up of 3 months. PH was defined as a mean pulmonary artery pressure (mPAP)\u2009&gt;\u200920\u2009mmHg and was subclassified by mean pulmonary artery wedge pressure (mPAWP) and pulmonary vascular resistance (PVR). The PH follow\u2010up probability was assessed by peak tricuspid regurgitant velocity and indirect PH signs. At baseline, 143\/274 (52%) patients had any PH: 40 had isolated post\u2010capillary, 65 had combined pre\u2010 and post\u2010capillary (CpcPH), 27 had pre\u2010capillary, and 11 had unclassified PH. Follow\u2010up PH probability was low in 149, intermediate in 73, or high in 42 patients. There was a progressive increase in baseline mPAP, mPAWP, and PVR (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001 for all) in patients with low, intermediate or high follow\u2010up PH probability. Patients with baseline CpcPH had a nearly 11\u2010fold higher risk (odds ratio 10.7) for a high follow\u2010up PH probability compared to those without PH. In conclusion, in MR patients the hemodynamic constellation according to the 2022 ESC\/ERS PH definition predicts the PH probability several months after a mitral valve procedure.\n                  <\/jats:p>","DOI":"10.1002\/pul2.70265","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T10:27:33Z","timestamp":1770892053000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of Right Heart Catheterization and the 2022 ESC\/ERS Definition of Pulmonary Hypertension in Patients With Mitral Regurgitation Undergoing Valve Repair\/Replacement"],"prefix":"10.1002","volume":"16","author":[{"given":"Mark","family":"G\u00fcpfert","sequence":"first","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"},{"name":"Cardiology Department University Hospital Z\u00fcrich  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"},{"name":"Department of Cardiology and Cardio\u2010Vascular Surgery H\u00f4pital Cardiologique de Haut\u2010L\u00e9v\u00eaque, Bordeaux University Hospital  France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp K.","family":"Haager","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Baier","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Kopp","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Rigger","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joannis","family":"Chronis","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Gerhard","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"},{"name":"Cardiology Department See\u2010Spital Horgen Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Rickli","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7036-5791","authenticated-orcid":false,"given":"Micha T.","family":"Maeder","sequence":"additional","affiliation":[{"name":"Department of Cardiology HOCH Health Ostschweiz, Kantonsspital St. Gallen  Switzerland"},{"name":"University of Basel  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