{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:43:34Z","timestamp":1793029414720,"version":"4.5.0"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T00:00:00Z","timestamp":1785110400000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pulm. circ."],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Abnormal pulmonary hemodynamics during exercise may persist even after balloon pulmonary angioplasty (BPA) for inoperable chronic thromboembolic pulmonary hypertension (CTEPH). We report two female patients who underwent long\u2010term supervised outpatient cardiac rehabilitation (CR) after BPA with continuous pulmonary vasodilators. In Case 1, training was performed at an intensity close to the anaerobic threshold. In Case 2, high\u2010intensity interval training (HIIT) was gradually introduced. Exercise right heart catheterization was used for serial assessment of the mean pulmonary arterial pressure\/cardiac output slope (mPAP\/CO slope). Functional outcomes were also evaluated by cardiopulmonary exercise testing. No adverse events occurred during follow\u2010up. The mPAP\/CO slope improved from 6.28 to 4.06\u2009mmHg\/L\/min at 12 months in Case 1 and from 8.40 to 6.71\u2009mmHg\/L\/min at 18 months in Case 2. Peak VO\n                    <jats:sub>2<\/jats:sub>\n                    also increased from 16.2 to 20.2\u2009mL\/kg\/min in Case 1 and from 18.3 to 24.9\u2009mL\/kg\/min in Case 2. Long\u2010term supervised outpatient CR after BPA appears to be feasible and may improve exercise pulmonary hemodynamics and exercise capacity.\n                  <\/jats:p>","DOI":"10.1002\/pul2.70359","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T08:25:16Z","timestamp":1785140716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010Term Supervised Cardiac Rehabilitation After Balloon Pulmonary Angioplasty Improved Residual Exercise Pulmonary Hypertension in Patients With Chronic Thromboembolic Pulmonary Hypertension: A Two\u2010Case Report"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4173-8859","authenticated-orcid":false,"given":"Yuya","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2461-7174","authenticated-orcid":false,"given":"Yoshihisa","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Cardiology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiro","family":"Okazaki","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momoko","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Yoshimori","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Tsunoda","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Cardiology Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toko","family":"Mitsui","sequence":"additional","affiliation":[{"name":"Department of Cardiology Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8924-1916","authenticated-orcid":false,"given":"Shiro","family":"Adachi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Nagoya University Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Cardiology Federation of National Public Service Personnel Mutual Aid Associations Meijo Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00879-2022"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01982-2019"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03181-2021"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0000000000000174"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2015-309230"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(25)00127-4"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0248-2021"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000512316"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1086\/690553"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.052899"}],"container-title":["Pulmonary Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pul2.70359","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pul2.70359","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pul2.70359","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T15:31:53Z","timestamp":1793028713000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pul2.70359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/pul2.70359"],"URL":"https:\/\/doi.org\/10.1002\/pul2.70359","archive":["Portico"],"relation":{},"ISSN":["2045-8940","2045-8940"],"issn-type":[{"value":"2045-8940","type":"print"},{"value":"2045-8940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-03-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70359"}}