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In male and female animals, sFUS reduces pulmonary CD8+ T cells and CD68+ macrophages, and reduces splenic monocytes. Splenic single\u2010cell transcriptomic analysis\u00a0in the SU5416\/hypoxia model revealed sex\u2010specific immune responses, including persistent interferon signaling in males.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pul2.70392","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:44:51Z","timestamp":1789145091000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Splenic Focused Ultrasound Improves Experimental Pulmonary Hypertension and Reprograms Immune Responses in Female and Male Rats"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1143-2293","authenticated-orcid":false,"given":"Alexandra","family":"Bekiaridou","sequence":"first","affiliation":[{"name":"Northwell Health New Hyde Park New York USA"},{"name":"Elmezzi Graduate School of Molecular Medicine, Northwell Health Manhasset New York USA"},{"name":"Institute of 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