{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T08:06:06Z","timestamp":1771661166331,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T00:00:00Z","timestamp":1644883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7192211"],"award-info":[{"award-number":["7192211"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Rheumatology &amp;amp; Autoimmunity"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We examined attitudes toward the COVID\u201019 vaccine, potential factors underlying these attitudes, and ways to increase vaccination willingness in autoimmune inflammatory rheumatic diseases (AIIRD) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A multicenter, web\u2010based, observational survey using an online questionnaire was conducted among AIIRD patients aged \u226518 years from May 24, 2021, to June 3, 2021. Participants were 3104 AIIRD patients (2921 unvaccinated and 183 vaccinated).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the unvaccinated patients, 32.9% were willing to receive the COVID\u201019 vaccine, 45.0% were uncertain, and 14.8% were unwilling. When vaccination was recommended by physicians, patients' willingness increased to 93.8%. Participants' main concerns were that the vaccine may aggravate AIIRD disease (63.0%) and may cause vaccine\u2010related adverse events (19.9%). Female patients were less likely to be vaccinated. However, patients who had children aged \u226418 years were more willing to be vaccinated. In addition, vaccination willingness was higher in patients with trust in the safety and efficacy of the COVID\u201019 vaccine. Notably, 183 (5.9%) patients were vaccinated. The major vaccination side effects were injection reaction, myalgia, and fatigue. At a median follow\u2010up of 88 (38, 131) days, patients' disease activities were stable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The findings show that AIIRD patients were unwilling to receive the COVID\u201019 vaccine because of fears of potential disease exacerbation and additional adverse events. Sociodemographic characteristics and concerns about COVID\u201019 disease and vaccines had a significant effect on vaccination willingness.<\/jats:p><\/jats:sec>","DOI":"10.1002\/rai2.12028","type":"journal-article","created":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T09:51:40Z","timestamp":1644918700000},"page":"82-91","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The COVID\u201019 vaccine: Attitudes and vaccination in patients with autoimmune inflammatory rheumatic diseases"],"prefix":"10.1002","volume":"2","author":[{"given":"Jiali","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"},{"name":"Department of Rheumatology and Immunology, The Second Xiangya Hospital Central South University  Changsha China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenxin","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunshan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuebo","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Tang","sequence":"additional","affiliation":[{"name":"Tsinghua Research Center for Public Health Tsinghua University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsr2105280"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/JAC.0000000000000360"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1124-9"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2014.206"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-215882"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(21)00039-4"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.15543"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30831-8"},{"issue":"10","key":"e_1_2_11_10_1","first-page":"e60","article-title":"American College of Rheumatology Guidance for COVID\u201019 vaccination in patients with rheumatic and musculoskeletal diseases: version 3","volume":"73","author":"Garg M","year":"2021","journal-title":"Arthritis Rheumatol"},{"issue":"10","key":"e_1_2_11_11_1","first-page":"60","article-title":"Recommendations and barriers to vaccination in systemic lupus erythematosus","volume":"17","author":"Curtis JR","year":"2018","journal-title":"Autoimmun Rev"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-215086"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa243"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2101544"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2103055"}],"container-title":["Rheumatology &amp; Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rai2.12028","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rai2.12028","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rai2.12028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T10:55:51Z","timestamp":1712746551000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rai2.12028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,15]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/rai2.12028"],"URL":"https:\/\/doi.org\/10.1002\/rai2.12028","archive":["Portico"],"relation":{},"ISSN":["2767-1410","2767-1429"],"issn-type":[{"value":"2767-1410","type":"print"},{"value":"2767-1429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,15]]},"assertion":[{"value":"2021-12-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}