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Recovery of\n                    <jats:sup>13<\/jats:sup>\n                    C in breath CO\n                    <jats:sub>2<\/jats:sub>\n                    is incomplete (&lt;50%) owing to sequestration of\n                    <jats:sup>13<\/jats:sup>\n                    C into organic molecules via the tricarboxylic acid (TCA) cycle. In addition lack of knowledge of CO\n                    <jats:sub>2<\/jats:sub>\n                    production rate (\n                    <jats:italic>V<\/jats:italic>\n                    CO\n                    <jats:sub>2<\/jats:sub>\n                    ) during the test leads to errors in the calculated percentage dose recovered (PDR).\n                    <jats:sup>2<\/jats:sup>\n                    H sequestration into organic molecules is low (\u223c4%) and is not influenced by factors that affect\n                    <jats:italic>V<\/jats:italic>\n                    CO\n                    <jats:sub>2<\/jats:sub>\n                    such as food intake or physical activity. After oxidation of\n                    <jats:sup>2<\/jats:sup>\n                    H\u2010labelled macromolecules, the label appears in body water, which can be sampled non\u2010invasively in urine or saliva. After an overnight fast, two healthy adults consumed [\n                    <jats:sup>2<\/jats:sup>\n                    H]MTG (1,3\u2010distearyl, 2\u2010[\n                    <jats:sup>2<\/jats:sup>\n                    H\n                    <jats:sub>15<\/jats:sub>\n                    ]octanoyl glycerol) and [\n                    <jats:sup>13<\/jats:sup>\n                    C]MTG (1,3 distearyl, 2\u2010[1\u2010\n                    <jats:sup>13<\/jats:sup>\n                    C]octanoyl glycerol) simultaneously. Total body water (TBW) was measured by\n                    <jats:sup>18<\/jats:sup>\n                    O dilution and also estimated from height and weight. Urine and saliva were sampled at baseline and for 10\u2009h after consumption of the test meal. The abundance of\n                    <jats:sup>2<\/jats:sup>\n                    HOH and H\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>18<\/jats:sup>\n                    O in urine and saliva was measured by continuous\u2010flow isotope\u2010ratio mass spectrometry. Cumulative PDR of\n                    <jats:sup>2<\/jats:sup>\n                    H and\n                    <jats:sup>18<\/jats:sup>\n                    O was calculated from the plateau enrichment, which was reached by 6\u2009h in both saliva and urine. Recovery of\n                    <jats:sup>2<\/jats:sup>\n                    H calculated using measured TBW was compared with that using an estimated value of TBW. Mean recovery of\n                    <jats:sup>2<\/jats:sup>\n                    H in saliva was 99.3% and in urine was 96.4%. Errors introduced by estimating TBW were &lt;5%. [\n                    <jats:sup>2<\/jats:sup>\n                    H]MTG could provide a simpler, more robust, indirect test of intraluminal fat digestion compared with the\n                    <jats:sup>13<\/jats:sup>\n                    C\u2010breath test. Further studies are required in pancreatic insufficient patients. Copyright \u00a9 2005 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/rcm.2278","type":"journal-article","created":{"date-parts":[[2005,12,6]],"date-time":"2005-12-06T07:22:20Z","timestamp":1133853740000},"page":"75-80","source":"Crossref","is-referenced-by-count":4,"title":["Advantages of deuterium\u2010labelled mixed triacylglycerol in studies of intraluminal fat digestion"],"prefix":"10.1002","volume":"20","author":[{"given":"Christine","family":"Slater","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Preston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence T.","family":"Weaver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,6]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1994.tb04399.x"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0261-5614(95)80012-3"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.76.4.349"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2125.1997.00589.x"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.77.3.239"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2000.tb02754.x"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1079\/PNS19990004"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.1998.tb00808.x"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(89)91632-6"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601637"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000201477"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365529850170946"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/fn.80.3.F183"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-200105000-00017"},{"issue":"3","key":"e_1_2_7_16_2","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1177\/15648265020233S109","volume":"23","author":"Slater C","year":"2002","journal-title":"Food Nutr. 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