{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:35:35Z","timestamp":1763746535858,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2006,6,22]],"date-time":"2006-06-22T00:00:00Z","timestamp":1150934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rapid Comm Mass Spectrometry"],"published-print":{"date-parts":[[2006,7,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The detection and identification of degradation products of scheduled chemicals, which are characteristic markers of Chemical Warfare agents (CWAs), plays a key role in verification analysis. Identification of such non\u2010scheduled but specific markers of CWAs helps in deciphering the kind of agent that was present in the sample submitted for off\u2010site analysis. This paper describes the stability of\n                    <jats:italic>N,N<\/jats:italic>\n                    \u2010dialkylaminoethyl\u20102\u2010chlorides, which are precursors for highly toxic chemicals like VX, in different solvents. These compounds are stable in chloroform, acetonitrile, hexane and dichloromethane but tend to undergo\n                    <jats:italic>in situ<\/jats:italic>\n                    nucleophilic substitution reaction in the presence of alcohols giving the corresponding alkyl ether. The study shows that\n                    <jats:italic>N,N<\/jats:italic>\n                    \u2010dialkylaminoethyl alkyl ethers can be used as markers of\n                    <jats:italic>N,N<\/jats:italic>\n                    \u2010dialkylaminoethyl\u20102\u2010chlorides. A detailed degradation study of these compounds in the presence of alcohols was carried out and it was found that the reaction follows pseudo\u2010first order kinetics. Electron ionization mass spectral data for the methyl ethers of all the compounds are briefly discussed. Copyright \u00a9 2006 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/rcm.2581","type":"journal-article","created":{"date-parts":[[2006,6,22]],"date-time":"2006-06-22T06:04:04Z","timestamp":1150956244000},"page":"2209-2214","source":"Crossref","is-referenced-by-count":10,"title":["<i>In situ<\/i>\n                    nucleophilic substitution reaction of\n                    <i>N,N<\/i>\n                    \u2010dialkylaminoethyl\u20102\u2010chlorides monitored by gas chromatography\/mass spectrometry"],"prefix":"10.1002","volume":"20","author":[{"given":"V. V. S.","family":"Lakshmi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. 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S.","family":"Murty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Prabhakar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Vairamani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,6,22]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"899","volume-title":"Encyclopedia of Analytical Chemistry","author":"Mesilaakso M","year":"2000"},{"key":"e_1_2_6_3_2","unstructured":"Organization for the Prohibition of Chemical Weapons (OPCW).Convention on the prohibition of the development production stockpiling and use of chemical weapons and on their destruction Organization for the Prohibition of Chemical Weapons (OPCW): The Hague 1994."},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(99)00754-2"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/12.11.625"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)01190-0"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(85)80005-4"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)94599-0"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2003.12.008"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)92665-2"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/oms.1210140506"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(02)01426-7"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.10.066"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/la047933j"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00487083"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9888(200012)35:12<1460::AID-JMS82>3.0.CO;2-J"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.962"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/jms.946"},{"key":"e_1_2_6_19_2","first-page":"792","author":"Tchoubar B","year":"1947","journal-title":"Bull. Soc. Chim. 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