{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:32:40Z","timestamp":1788870760509,"version":"build-2803163510"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2001,4,18]],"date-time":"2001-04-18T00:00:00Z","timestamp":987552000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Proyectos Alma Mater, Cuba"},{"DOI":"10.13039\/501100008737","name":"DGESIC","doi-asserted-by":"crossref","award":["PB98-0018"],"award-info":[{"award-number":["PB98-0018"]}],"id":[{"id":"10.13039\/501100008737","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008737","name":"DGESIC","doi-asserted-by":"crossref","award":["PB98-0803"],"award-info":[{"award-number":["PB98-0803"]}],"id":[{"id":"10.13039\/501100008737","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rapid Comm Mass Spectrometry"],"published-print":{"date-parts":[[2001,5,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The electrospray ionisation (ESI) in negative mode of the pharmacologically significant 3,5\u2010disubstituted tetrahydro\u20102\n                    <jats:italic>H<\/jats:italic>\n                    \u20101,3,5\u2010thiadiazin\u20102\u2010thiones, and their subsequent fragmentations using an ion\u2010trap mass spectrometer, have been investigated. Experiments on sequential product ion fragmentations (MS\n                    <jats:sup>n<\/jats:sup>\n                    ) were performed in order to elucidate the degradation pathways for these compounds. The data presented show that the fragmentation of the even\u2010electron [M\u2005\u2212\u2005H]\n                    <jats:sup>\u2212<\/jats:sup>\n                    ions could proceed through an internal nucleophilic substitution displacement. Decarboxylation and extrusion of carbon disulfide are other fragmentations observed. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/rcm.294","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T16:24:15Z","timestamp":1030292655000},"page":"758-762","source":"Crossref","is-referenced-by-count":8,"title":["A study of the electrospray ionisation and ion\u2010trap fragmentation of [M\u2005\u2212\u2005H]\n                    <sup>\u2212<\/sup>\n                    ions of new 3,5\u2010disubstituted tetrahydro\u20102\n                    <i>H<\/i>\n                    \u20101,3,5\u2010thiadiazin\u20102\u2010thiones"],"prefix":"10.1002","volume":"15","author":[{"given":"Roberto","family":"Mart\u00ednez\u2010Alvarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazario","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Seoane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarita","family":"Su\u00e1rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolando","family":"P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hortensia","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nour","family":"Kayali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,4,19]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"121","volume":"21","author":"Zolnai T","year":"1971","journal-title":"Arzneim.\u2010Forsch.\/Drug Res."},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.19903230910"},{"key":"e_1_2_6_4_2","first-page":"787","volume":"50","author":"Ilhan E","year":"1995","journal-title":"Il Farmaco"},{"key":"e_1_2_6_5_2","first-page":"160","volume":"42","author":"Ertan M","year":"1992","journal-title":"Arzneim.\u2010Forsch.\/Drug Res."},{"key":"e_1_2_6_6_2","first-page":"1807","volume":"19","author":"Schorr M","year":"1969","journal-title":"Arzneim.\u2010Forsch.\/Drug Res."},{"key":"e_1_2_6_7_2","first-page":"244","volume":"54","author":"Aboul\u2010Fald T","year":"1999","journal-title":"Pharmazie"},{"key":"e_1_2_6_8_2","first-page":"764","volume":"49","author":"Ochoa C","year":"1999","journal-title":"Arzneim.\u2010Forsch.\/Drug Res."},{"key":"e_1_2_6_9_2","first-page":"854","volume":"50","author":"P\u00e9rez R","year":"2000","journal-title":"Arzneim.\u2010Forsch.\/Drug Res."},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(99)02167-X"},{"key":"e_1_2_6_11_2","volume-title":"Mass Spectrometry of Heterocyclic Compounds","author":"Porter QN","year":"1985"},{"key":"e_1_2_6_12_2","first-page":"222","volume":"39","author":"Molero\u2010Vilchez MD","year":"2001","journal-title":"Org. 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