{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T14:49:42Z","timestamp":1789224582201,"version":"build-2803163510"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,1,6]],"date-time":"2009-01-06T00:00:00Z","timestamp":1231200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003451","name":"Universidad del Pa\u00eds Vasco","doi-asserted-by":"crossref","award":["15978\/2004"],"award-info":[{"award-number":["15978\/2004"]}],"id":[{"id":"10.13039\/501100003451","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rapid Comm Mass Spectrometry"],"published-print":{"date-parts":[[2009,2,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Liquid chromatography coupled with a photodiode array detector, electrospray ionization, collision\u2010induced dissociation and tandem mass spectrometry (LC\u2010DAD\/ESI\u2010CID\u2010MS\/MS) on a triple quadrupole (QqQ) has been used to detect and characterize polyphenols and methylxanthines in green coffee beans: three phenolic acids (caffeic acid, ferulic acid and dimethoxycinnamic acid), three isomeric caffeoylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    354), three feruloylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    368), one\n                    <jats:italic>p\u2010<\/jats:italic>\n                    coumaroylquinic acid (M\n                    <jats:sub>r<\/jats:sub>\n                    338), three dicaffeoylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    516), three feruloyl\u2010caffeoylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    530), four\n                    <jats:italic>p\u2010<\/jats:italic>\n                    coumaroyl\u2010caffeoylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    500), three diferuloylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    544), six dimethoxycinnamoyl\u2010caffeoylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    544), three dimethoxycinnamoyl\u2010feruloylquinic acids (M\n                    <jats:sub>r<\/jats:sub>\n                    558), six cinnamoyl\u2010amino acid conjugates, three cinnamoyl glycosides, and three methylxanthines (caffeine, theobromine and theophylline). Dimethoxycinnamic acid, three isomers of dimethoxycinnamoyl\u2010caffeoylquinic acids and another three of dimethoxycinnamoyl\u2010feruloylquinic acids, as well as the three cinnamoyl glycosides, had not previously been reported in coffee beans. Structures have been assigned on the basis of the complementary information obtained from UV\u2010visible spectra, relative hydrophobicity, scan mode MS spectra, and fragmentation patterns in MS\n                    <jats:sup>2<\/jats:sup>\n                    spectra (both in the positive and negative ion modes) obtained using a QqQ at different collision energies. A structure diagnosis scheme is provided for the identification of different isomers of polyphenols and methylxanthines. Copyright \u00a9 2009 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/rcm.3884","type":"journal-article","created":{"date-parts":[[2009,1,6]],"date-time":"2009-01-06T09:46:22Z","timestamp":1231235182000},"page":"363-383","source":"Crossref","is-referenced-by-count":75,"title":["Liquid chromatography coupled with ultraviolet absorbance detection, electrospray ionization, collision\u2010induced dissociation and tandem mass spectrometry on a triple quadrupole for the on\u2010line characterization of polyphenols and methylxanthines in green coffee beans"],"prefix":"10.1002","volume":"23","author":[{"given":"Rosa Maria","family":"Alonso\u2010Salces","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Guillou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Berrueta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,1,6]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"314","volume-title":"Methods in Polyphenol Analysis","author":"Clifford MN","year":"2003"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/40.1.45"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2005.01.064"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2003.12.020"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf026187q"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/jf050046h"},{"key":"e_1_2_6_8_2","volume":"54","author":"Clifford MN","year":"2006","journal-title":"J. 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