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The analytes were oxidized with chromium(VI) oxide and the resulting carboxylic and ethoxy\u2010carboxylic acids were isolated by extraction with ethyl acetate; the extracts were alkalinized and infused into the ESI\u2010MS system working in the negative\u2010ion mode. The yields of the combined oxidation\u2010extraction were ca. 100% for non\u2010ethoxylated fatty alcohols dissolved in acetone and they decreased moderately in samples containing increasing amounts of water (e.g., a 75% yield was obtained with 50% water). Ethoxylated alcohols with more than two ethylene oxide units resulted in yields of ca. 60%. Low limits of detection (LODs) were obtained when the procedure was applied to the analysis of body\u2010care products and cosmetics containing fatty alcohols, e.g., in a varicose\u2010vein cream, the LODs were 25 \u00b5g cetyl alcohol and 7.5 \u00b5g stearyl alcohol (detected as palmitic acid and stearic acid, respectively) per gram of sample. High molecular mass alcohols were also detected in seawater after pre\u2010concentration by solid\u2010phase extraction. Thus, the proposed method is particularly valuable for use in industrial samples having complex matrices and in environmental samples and it is competitive with other methods for the analysis of trace amounts of fatty alcohols. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/rcm.4624","type":"journal-article","created":{"date-parts":[[2010,6,16]],"date-time":"2010-06-16T23:38:11Z","timestamp":1276731491000},"page":"2093-2100","source":"Crossref","is-referenced-by-count":5,"title":["Chromium(VI) oxide oxidation of non\u2010ethoxylated and ethoxylated alcohols for determination by electrospray ionization mass spectrometry"],"prefix":"10.1002","volume":"24","author":[{"given":"Miriam","family":"Beneito\u2010Cambra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Bernab\u00e9\u2010Zaf\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernesto F.","family":"Sim\u00f3\u2010Alfonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Ramis\u2010Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,6,16]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"175","volume-title":"Waxes: Chemistry, Molecular Biology and Functions","author":"Bianchi G","year":"1995"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/9780470988596"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1201\/9780203911334"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/je0503857"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00295a004"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00107a008"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(01)00030-3"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/jms.234"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)95035-0"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)95975-8"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(02)01956-8"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(02)00076-6"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac9709155"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)82019-7"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02490702"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/10826079608006299"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02490474"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/10408349608050563"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2006.03.093"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(96)00009-X"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02540636"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00119a033"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(94)00615-6"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(96)00613-9"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(95)01290-7"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(97)00139-8"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2004.02.006"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2003.08.091"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00010a022"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(92)80165-Q"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2004.05.013"},{"key":"e_1_2_6_33_2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1515\/tsd-2003-400104","volume":"40","author":"Bachus H","year":"2003","journal-title":"Tens. 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