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The structure was determined by electrospray mass spectrometry and synthesis. The major component of the skin secretion is the analogous tryptophyllin peptide FPWL(NH\n                    <jats:sub>2<\/jats:sub>\n                    ). Both peptides show opioid activity at 10\n                    <jats:sup>\u20137<\/jats:sup>\n                    \u2009M, and are likely to act via the \u03bc opioid receptor. Copyright \u00a9 2011 John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/rcm.5041","type":"journal-article","created":{"date-parts":[[2011,5,20]],"date-time":"2011-05-20T09:13:04Z","timestamp":1305882784000},"page":"1735-1740","source":"Crossref","is-referenced-by-count":14,"title":["An unusual kynurenine\u2010containing opioid tetrapeptide from the skin gland secretion of the Australian red tree frog\n                    <i>Litoria rubella<\/i>\n                    . Sequence determination by electrospray mass spectrometry"],"prefix":"10.1002","volume":"25","author":[{"given":"Simon T.","family":"Ellis\u2010Steinborner","sequence":"first","affiliation":[{"name":"Department of Chemistry The University of Adelaide  South Australia 5005"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Scanlon","sequence":"additional","affiliation":[{"name":"Department of Chemistry The University of Adelaide  South Australia 5005"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian F.","family":"Musgrave","sequence":"additional","affiliation":[{"name":"School of Medical Sciences The University of Adelaide  South Australia 5005"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. T. 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