{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:41:20Z","timestamp":1792093280806,"version":"4.4.0"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T00:00:00Z","timestamp":1767052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373626"],"award-info":[{"award-number":["82373626"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Rapid Comm Mass Spectrometry"],"published-print":{"date-parts":[[2026,3,30]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>Chemicals migrating from plastic and take\u2010out food packaging can leach into food, posing inherent health risks to consumers. Given the ubiquitous use of plastic packaging in daily diets, reliable analytical methods for detecting restricted substances in food contact materials are imperative for safeguarding public health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A novel analytical method, coupling gas chromatography\u2013mass spectrometry (GC\u2013MS) with liquid\u2013liquid extraction for sample pretreatment, was established for the simultaneous separation and quantification of 15 common restricted substances (10 plasticizers, 1 antioxidant, and 4 ultraviolet absorbers) migrating from food plastic packaging materials into food products.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The method exhibited excellent linearity (correlation coefficients,\n                      <jats:italic>r<\/jats:italic>\n                      \u2009&gt;\u20090.99) across wide concentration ranges, with limits of detection (LODs) ranging from 0.005 to 0.046\u2009mg\/L. Validation data showed average recoveries of 72.30%\u2013109.03% and relative standard deviations (RSDs,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096) of 1.13%\u201326.50%, confirming its analytical reliability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This method enables rapid and accurate determination of the 15 target restricted substances, facilitating migration monitoring in food plastic packaging and strengthening technical support for food safety assessment in daily and take\u2010out food contexts.<\/jats:p>\n                  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