{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:58:10Z","timestamp":1790927890597,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:00:00Z","timestamp":1787011200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Rapid Comm Mass Spectrometry"],"published-print":{"date-parts":[[2026,11,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>\n                      As a classic multiorigin herbal medicine, the precise authentication of\n                      <jats:italic>Curcumae Radix<\/jats:italic>\n                      (Yujin) is crucial for ensuring market standardization and clinical efficacy. Given the complexity of herbal materials, single\u2010method identification often lacks the resolution required to distinguish between closely related species or handle degraded with significant DNA degradation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A two\u2010dimensional analytical strategy was applied to 24 batches of\n                      <jats:italic>Curcumae Radix<\/jats:italic>\n                      samples. This approach combined ITS2 DNA barcoding for genetic identification with headspace gas chromatography\u2013ion mobility spectrometry (HS\u2010GC\u2010IMS) to analyze volatile organic compound (VOC) profiles. The resulting HS\u2010GC\u2010IMS data were processed using chemometric tools, including principal component analysis (PCA) and partial least squares\u2010discriminant analysis (PLS\u2010DA), to compare and differentiate the decoction pieces.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The results demonstrated that while ITS2 DNA barcoding effectively identified\n                      <jats:italic>Curcuma kwangsiensis<\/jats:italic>\n                      S. G. Lee et C. F. Liang, it failed to discriminate between the closely related species\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Curcuma longa<\/jats:italic>\n                      <\/jats:styled-content>\n                      L. and\n                      <jats:italic>Curcuma phaeocaulis<\/jats:italic>\n                      Val. and was ineffective for DNA\u2010degraded samples of\n                      <jats:italic>Curcuma wenyujin<\/jats:italic>\n                      Y. H. Chen et C. Ling. Conversely, HS\u2010GC\u2010IMS successfully established distinct VOC fingerprints for each source. When coupled with chemometric analysis, this method pinpointed specific interspecific discriminatory biomarkers that allowed for clear differentiation where genetic barcoding fell short.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      By integrating stable genetic information with volatile chemical fingerprints, this study establishes a complementary two\u2010dimensional identification system. This strategy provides an innovative and reliable solution for the botanical authentication and quality control of\n                      <jats:italic>Curcumae Radix<\/jats:italic>\n                      , offering a broadly applicable paradigm for the precise identification of other complex herbal materials.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/rcm.70160","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T03:16:26Z","timestamp":1787109386000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Authentication of the Botanical Origins of\n                    <scp>\n                      <i>Curcumae Radix<\/i>\n                    <\/scp>\n                    Based on DNA Barcoding and 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Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Han","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Engineering of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Yong","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Engineering of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Run","family":"Sun","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Engineering of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin 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Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beibei","family":"Xiang","sequence":"additional","affiliation":[{"name":"College of Chinese Materia Medica of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3194-0383","authenticated-orcid":false,"given":"Heshui","family":"Yu","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Engineering of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"},{"name":"Haihe Laboratory of Modern Chinese Medicine Tianjin University of Traditional Chinese Medicine  Tianjin China"},{"name":"Tianjin Key Laboratory of Intelligent and Green Pharmaceuticals for Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine  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