{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:00Z","timestamp":1753870140595,"version":"3.41.2"},"reference-count":8,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T00:00:00Z","timestamp":1660003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 59\u2010year\u2010old woman complained of continuous dyspnea. Computed tomography revealed multiple pulmonary nodules, mildly small enlarged mediastinal lymph nodes and a nodule in the liver segment 8. Her dyspnea worsened with respiratory failure 4\u2009days after presentation. Liver biopsy was not possible as she could not hold her breath; thus, we performed bronchoscopy. For biopsy, the pulmonary nodules with a positive bronchus sign were preferred over the mildly small enlarged mediastinal lymph nodes. Bronchoscopy under non\u2010invasive positive pressure ventilation (<jats:styled-content style=\"fixed-case\">NPPV<\/jats:styled-content>) or high\u2010flow nasal cannula (<jats:styled-content style=\"fixed-case\">HFNC<\/jats:styled-content>) was impossible because of the lack of equipment. Therefore, we biopsied via thin bronchoscope through nasal cavity under a high\u2010concentration oxygen mask. Pathological findings revealed epidermal growth factor receptor mutation\u2010positive lung adenocarcinoma. For patients with respiratory failure who cannot undergo bronchoscopy under <jats:styled-content style=\"fixed-case\">NPPV<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">HFNC<\/jats:styled-content>, thin bronchoscopy through the nasal cavity under a high\u2010concentration oxygen mask may be clinically useful to prevent hypoxaemia during the procedure<\/jats:p>","DOI":"10.1002\/rcr2.1007","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T07:25:09Z","timestamp":1660029909000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidermal growth factor receptor mutation\u2010positive advanced lung adenocarcinoma presenting with acute respiratory failure diagnosed by thin bronchoscope through transnasal route under high\u2010concentration oxygen 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