{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:50:00Z","timestamp":1756461000028,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T00:00:00Z","timestamp":1663459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>IgG4\u2010related disease is characterized by a systemic fibroinflammatory process associated with substantial infiltration by plasma cells with IgG4 in the organs. Our patient presented with pleural effusion, and was diagnosed with IgG4\u2010related lung disease (IgG4\u2010RLD) after he received two doses of the Pfizer COVID\u201019 vaccine. The patient developed dyspnea and hypoxia 2\u2009weeks after receiving the second dose of the Pfizer COVID\u201019 vaccine. CT scan revealed left pleural effusion which was drained. However, the effusion recurred requiring thoracoscopic drainage, placement of an indwelling catheter, and decortication with biopsy. IgG4 serum level was 268\u2009mg\/dl and pathology revealed pleural fibrosis, lymphoplasmacytic infiltrates, and increased IgG4\u2010positive plasma cells with no malignant cells leading to a diagnosis of IgG4\u2010RLD. Although COVID vaccine\u2010related IgG4\u2010RLD is a novel finding, having a high degree of suspicion following vaccination is always important for early diagnosis and effective treatment.<\/jats:p>","DOI":"10.1002\/rcr2.1026","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T06:44:05Z","timestamp":1663569845000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["<scp>IgG4<\/scp> related pleural disease: Recurrent pleural effusion after <scp>COVID<\/scp>\u201019 vaccination"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0334-4776","authenticated-orcid":false,"given":"Saria","family":"Tasnim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Texas Tech University Health Sciences Center  Amarillo Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ola","family":"Al\u2010Jobory","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Texas Tech University Health Sciences Center  Amarillo Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Hallak","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine Ochsner Medical Center  New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taru","family":"Bharadwaj","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Texas Tech University Health Sciences Center  Amarillo Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Texas Tech University Health Sciences Center  Amarillo Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S315727"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2021.06.002"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.617089"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00025211"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201403-128FR"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1026","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.1026","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T23:43:25Z","timestamp":1692661405000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.1026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,18]]},"references-count":5,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/rcr2.1026"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.1026","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2022,9,18]]},"assertion":[{"value":"2022-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01026"}}