{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:06Z","timestamp":1753870146043,"version":"3.41.2"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pulmonary leiomyoma has a diverse clinical spectrum of disease. Here we describe two patients with vastly different presentations. The first case is a 23\u2010year\u2010old female with a chronic cough and no visible tracheal lesion on computer tomography (CT) chest imaging. Flexible bronchoscopy revealed a small tracheal nodule, with histopathology confirming pulmonary leiomyoma. The second case is a 57\u2010year\u2010old female with a painless abdominal mass. CT imaging revealed widespread lung \u2018cannonball\u2019 nodules. Percutaneous biopsy confirmed metastatic leiomyoma. After progression on surveillance and endocrine therapy, she was commenced on doxorubicin with interval radiological improvement. These cases highlight the clinical heterogeneity in this disease, and thus, complexity in devising standardized diagnostic and therapeutic protocols.<\/jats:p>","DOI":"10.1002\/rcr2.1088","type":"journal-article","created":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T07:50:32Z","timestamp":1675151432000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The panorama of pulmonary leiomyoma: A tale of two tumours"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8127-0218","authenticated-orcid":false,"given":"Ajit","family":"Nair","sequence":"first","affiliation":[{"name":"Monash Lung Sleep Allergy and Immunology Monash Health  Melbourne Victoria Australia"},{"name":"School of Clinical Sciences Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7409-9328","authenticated-orcid":false,"given":"Paul","family":"Leong","sequence":"additional","affiliation":[{"name":"Monash Lung Sleep Allergy and Immunology Monash Health  Melbourne Victoria Australia"},{"name":"School of Clinical Sciences Monash University  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.14.13946"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02015238"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-0679(03)70013-6"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.12525"},{"issue":"4","key":"e_1_2_10_6_1","first-page":"e54\u2013e56","article-title":"Primary pulmonary leiomyoma: a first for peripheral diagnostic bronchoscopy?","volume":"27","author":"Abu\u2010Hishmeh M","year":"2020","journal-title":"J Bronchology Interv Pulmonol [Internet]"},{"key":"e_1_2_10_7_1","unstructured":"YaziciogluA SubasiM TurkkanS YekelerE.Chest wall leiomyomas: a case report and review of the literature 2016."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2011.03.051"},{"issue":"1","key":"e_1_2_10_9_1","first-page":"89","article-title":"Metastasizing fibroleiomyoma of the uterus: report of a case and review of the literature","volume":"15","author":"Steiner PE","year":"1939","journal-title":"Am J Pathol [Internet]"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.176.6.1761409"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0175875"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/OGX.0b013e3181d60f93"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(89)90207-4"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-032021"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.5090\/kjtcs.2017.50.1.59"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdy096"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1088","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.1088","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1088","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T12:33:08Z","timestamp":1692275588000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.1088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,30]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1002\/rcr2.1088"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.1088","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2023,1,30]]},"assertion":[{"value":"2022-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01088"}}