{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:09:10Z","timestamp":1753870150782,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Respirology Case Reports"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This case study reports the exercise ventilatory responses of a 17\u2010year\u2010old female who sustained a traumatic brain injury (TBI) which resulted in loss of consciousness. Subsequently, she suffered from post\u2010concussion syndrome accompanied by orthostatic and exercise intolerance. A cardiopulmonary exercise test (CPET) was performed 2\u2009years post\u2010TBI. The results demonstrated significant hypoventilation with elevated PetCO<jats:sub>2<\/jats:sub> and ventilatory equivalents, progressive desaturation, and pre\u2010syncope symptoms limiting exercise capacity. A repeat CPET 4\u2009years post\u2010TBI demonstrated a similar exercise capacity limited by pre\u2010syncope symptoms. However, there was a marked improvement in the ventilatory response, with appropriate ventilation, PetCO<jats:sub>2<\/jats:sub>, and ventilatory equivalents, and only minor desaturation near peak exercise. Hypoventilation during exercise has been reported in subjects with post\u2010concussion syndrome; however, with time the exercise ventilatory response can potentially normalize as observed in this subject.<\/jats:p>","DOI":"10.1002\/rcr2.1103","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T07:50:34Z","timestamp":1676620234000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Improved ventilatory response during exercise over time after concussion: A case report"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5299-7493","authenticated-orcid":false,"given":"Ryan","family":"Welch","sequence":"first","affiliation":[{"name":"Respiratory Services Te Whatu Ora Te Toka Tumai Auckland  Auckland New Zealand"},{"name":"Medicine The University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brooke","family":"Kelly","sequence":"additional","affiliation":[{"name":"Respiratory Services Te Whatu Ora Te Toka Tumai Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Whyte","sequence":"additional","affiliation":[{"name":"Respiratory Services Te Whatu Ora Te Toka Tumai Auckland  Auckland New Zealand"},{"name":"Medicine The University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Ellyett","sequence":"additional","affiliation":[{"name":"Respiratory Services Te Whatu Ora Te Toka Tumai Auckland  Auckland New Zealand"},{"name":"Medicine The University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clair","family":"King","sequence":"additional","affiliation":[{"name":"Respiratory Services Te Whatu Ora Te Toka Tumai Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-51.11.08"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/HTR.0000000000000145"},{"key":"e_1_2_8_4_1","first-page":"163","volume-title":"Translational research in traumatic brain injury","author":"Su YRS","year":"2016"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.12.030"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1985.62.2.0194"}],"container-title":["Respirology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1103","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/rcr2.1103","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/rcr2.1103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T12:32:37Z","timestamp":1692275557000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/rcr2.1103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,16]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1002\/rcr2.1103"],"URL":"https:\/\/doi.org\/10.1002\/rcr2.1103","archive":["Portico"],"relation":{},"ISSN":["2051-3380","2051-3380"],"issn-type":[{"type":"print","value":"2051-3380"},{"type":"electronic","value":"2051-3380"}],"subject":[],"published":{"date-parts":[[2023,2,16]]},"assertion":[{"value":"2023-01-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e01103"}}